| Category |
Oncology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Timing matters: Early vs late recurrence in nasopharyngeal carcinoma and its impact on survival
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jing-Bo Wang, Yang Meng, Mei-Lin He, Si-Jia Zhang, Xiao-Dong Huang, Ye Zhang, Run-Ye Wu, Kai Wang, Xue-Song Chen, Yuan Qu, Jiang-Hu Zhang, Qing-Feng Liu, Jing-Wei Luo, Li Gao, Jian-Ping Xiao, Ye-Xiong Li, Li-Hua Luo and Jun-Lin Yi |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Key Research and Development Program of China |
2023YFC2411602 |
| Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences |
2024-I2M-C&T-B-063 |
| Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences |
2024-I2M-C&T-A-006 |
| Beijing Hope Run Special Fund of Cancer Foundation of China |
LC2021L06 |
| National Natural Science Foundation of China |
81172125 |
|
| Corresponding Author |
Jun-Lin Yi, Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Panjiayuan Nanli, Beijing 100021, China. yijunlin1969@163.com |
| Key Words |
Nasopharyngeal carcinoma; Recurrence; Prognosis; Post-recurrence survival; Radiotherapy |
| Core Tip |
This is the core tip of our study focusing on recurrent nasopharyngeal carcinoma. In 330 recurrent patients, recurrence events peaked in the second year. Recurrence timing is a pivotal prognostic factor. Early locoregional recurrence within 24 months is indicative of significantly inferior post-recurrence overall survival, warranting more intensive surveillance and aggressive salvage strategies for this subset. |
| Citation |
Wang JB, Meng Y, He ML, Zhang SJ, Huang XD, Zhang Y, Wu RY, Wang K, Chen XS, Qu Y, Zhang JH, Liu QF, Luo JW, Gao L, Xiao JP, Li YX, Luo LH, Yi JL. Timing matters: Early vs late recurrence in nasopharyngeal carcinoma and its impact on survival. World J Clin Oncol 2026; In press
|
| PDF |
124227-in-press.pdf
|
