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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 124250
DOI 10.4251/wjgo.124250
Country China
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Preoperative cancer-inflammation-prognostic-index-based nomogram for overall survival in stage I-III gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Ning Chang, Li-Xiang Zhang, En-Ze Zhou, Zhi-Jian Wei and A-Man Xu
Funding Agency and Grant Number
Corresponding Author Zhi-Jian Wei, Professor, Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Hefei 230031, Anhui Province, China. yfy1041018@fy.ahmu.edu.cn
Key Words Gastric cancer; Cancer inflammation prognostic index; Overall survival; Nomogram; Prognosis; Systemic inflammation
Core Tip The Cancer Inflammation Prognostic Index (CIPI), calculated as carcinoembryonic antigen multiplied by the neutrophil-to-lymphocyte ratio, integrates tumour burden with systemic inflammation. In this retrospective cohort of 1071 patients with stage I-III gastric cancer undergoing radical gastrectomy, a high preoperative CIPI was independently associated with poorer overall survival and further stratified risk within tumour-node-metastasis stages. A CIPI-based nomogram showed modestly better discrimination than a reference T-N model and acceptable calibration on internal validation. CIPI may complement conventional staging, but external validation and prospective assessment are required before clinical implementation.
Citation Chang N, Zhang LX, Zhou EZ, Wei ZJ, Xu AM. Preoperative cancer-inflammation-prognostic-index-based nomogram for overall survival in stage I-III gastric cancer. World J Gastrointest Oncol 2026; In press
PDF 124250-in-press.pdf
Received
2026-06-10 08:36
Peer-Review Started
2026-06-10 08:36
First Decision by Editorial Office Director
Return for Revision
2026-07-09 08:05
Revised
2026-07-30 13:09
Publication Fee Transferred
2026-08-17 02:38
Second Decision by Editor
2026-09-15 02:45
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-09-15 09:30
Articles in Press
2026-09-15 09:30
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5204 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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