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Publication Name World Journal of Translational Medicine
Manuscript ID 124281
DOI 10.5528/wjtm.124281
Country United Kingdom
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Application of the fibrosis-4 score in a generalised population
Manuscript Source Unsolicited Manuscript
All Author List Hendrik F Conradie and Kate Shipman
Funding Agency and Grant Number
Corresponding Author Hendrik F Conradie, MD, Medicine, St Richard's Hospital, Spitalfield Lane, Chichester 01243 788122 PO19 6SE, Chichester PO19 6SE, West Sussex, United Kingdom. hendrik.conradie@nhs.net
Key Words Risk assessment; Liver fibrosis; Fatty liver; Non-alcoholic fatty liver disease; Metabolic dysfunction-associated steatotic liver disease
Core Tip The fibrosis-4 (FIB-4) score is used indiscriminately and when applied inappropriately may lead to misleading results and diagnostic noise. This study shows how different a generalised population is from the population on which the FIB-4 score was validated. Other adaptations of the FIB-4 score exist that have shown diagnostic superiority on specific populations which could be applied, even reflexively using artificial intelligence.
Citation Conradie HF, Shipman K. Application of the fibrosis-4 score in a generalised population. World J Transl Med 2026; In press
PDF 124281-in-press.pdf
Received
2026-06-11 03:41
Peer-Review Started
2026-06-11 03:41
First Decision by Editorial Office Director
Return for Revision
2026-07-13 20:35
Revised
2026-07-27 06:29
Publication Fee Transferred
Second Decision by Editor
2026-08-10 02:45
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-08-10 10:48
Articles in Press
2026-08-10 10:48
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-6132 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com