Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	124318
DOI	10.4240/wjgs.124318
Country	Palestine

Category	Surgery
Manuscript Type	Meta-Analysis
Article Title	Comparative efficacy of bowel preparation strategies in colorectal surgery: A network meta-analysis of randomized controlled trials
Manuscript Source	Unsolicited Manuscript
All Author List	Maha AbuZarifa, Mesan Hijazy, Asmaa Zakria Alnajjar, Omar Khaled Abdelsalam, Abdalrahman Ajjur, Mariam A Abusalah, Abdallah AbuJlambo, Mohammed B AbuZarifa, Ola AbuZarifa and Hazem Ayesh
Funding Agency and Grant Number
Corresponding Author	Maha AbuZarifa, MD, Faculty of Medicine, Al-Quds University, Al-Azhar Branch, Gaza P850, Palestine. 20200430@student.alazhar.edu.ps
Key Words	Surgical site infections; Preoperative cleansing; Antimicrobial prophylaxis; Colorectal surgery; Meta-analysis
Core Tip	This network meta-analysis provides a comprehensive comparison of bowel preparation strategies in colorectal surgery using data from 38 randomized controlled trials. Mechanical bowel preparation combined with oral antibiotics (OAB) significantly reduced incisional surgical site infection (relative risk 0.53, 95% confidence interval: 0.29-0.99) and organ-space surgical site infection (relative risk 0.62, 95% confidence interval: 0.39-0.99) compared with other regimens. OAB-containing approaches ranked highest for preventing postoperative infectious complications. These findings reinforce the superiority of combined mechanical bowel preparation + OAB as the optimal strategy and support current clinical recommendations while highlighting areas for further research.
Citation	AbuZarifa M, Hijazy M, Alnajjar AZ, Abdelsalam OK, Ajjur A, Abusalah MA, AbuJlambo A, AbuZarifa MB, AbuZarifa O, Ayesh H. Comparative efficacy of bowel preparation strategies in colorectal surgery: A network meta-analysis of randomized controlled trials. World J Gastrointest Surg 2026; In press DOI: https://doi.org/10.4240/wjgs.124318
PDF	124318-in-press.pdf

Received	2026-06-12 03:46
Peer-Review Started	2026-06-12 03:46
First Decision by Editorial Office Director
Return for Revision	2026-07-09 09:19
Revised	2026-07-21 04:42
Publication Fee Transferred
Second Decision by Editor	2026-09-30 02:47
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-09-30 07:39
Articles in Press	2026-09-30 07:39
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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