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Publication Name World Journal of Gastroenterology
Manuscript ID 124326
Country China
Category Oncology
Manuscript Type Retrospective Study
Article Title Prognostic value of triglyceride-glucose index in advanced esophageal squamous cell carcinoma treated with camrelizumab plus nab-paclitaxel and/or cisplatin
Manuscript Source Unsolicited Manuscript
All Author List Zi-Xuan Wei, Yan Wang, Jia-Yao Xu, Jie Yan and Yan-Ru Qin
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 82273381
Corresponding Author Yan-Ru Qin, MD, Department of Oncology, Zhengzhou University First Affiliated Hospital, No. 1 Longhu Zhonghuan Road, Jinshui District, Zhengzhou 450000, Henan Province, China. yanruqin@163.com
Key Words Triglyceride-glucose index; Esophageal squamous cell carcinoma; Immunotherapy; Chemotherapy; Insulin resistance; Objective response rate; Survival
Core Tip The triglyceride glucose (TyG) index is an emerging, easily accessible marker of insulin resistance that independently predicts poorer treatment response and survival in patients with advanced or metastatic esophageal squamous cell carcinoma undergoing immunotherapy with camrelizumab and chemotherapy (nab-paclitaxel/cisplatin). A high TyG index is significantly associated with a lower objective response rate (23.7% vs 55.6%) and worse progression-free survival and overall survival. The TyG index may aid in patient stratification and inform treatment decisions for advanced esophageal squamous cell carcinoma, potentially improving clinical outcomes.
Citation Wei ZX, Wang Y, Xu JY, Yan J, Qin YR. Prognostic value of triglyceride-glucose index in advanced esophageal squamous cell carcinoma treated with camrelizumab plus nab-paclitaxel and/or cisplatin. World J Gastroenterol 2026; In press
Received
2026-06-12 07:35
Peer-Review Started
2026-06-12 07:35
First Decision by Editorial Office Director
Return for Revision
2026-07-15 06:06
Revised
2026-07-31 13:41
Publication Fee Transferred
2026-08-26 03:44
Second Decision by Editor
2026-09-17 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-09-17 09:29
Articles in Press
2026-09-17 09:29
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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