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Articles in Press
10/14/2026 8:38:36 AM | Browse: 12 | Download: 2
| Category |
Oncology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Efficacy and safety of immune checkpoint inhibitors in the treatment of digestive system cancers: An umbrella review
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jun-Jie Yu, Li Zhu, Xiang-Peng Li, Lu-Ping Wang, Fan-Gang Meng, Wen-Xia Sui, Xiao-Jie Feng, Ying-Ying Sui, Ping Leng and Jun-Min Yu |
| Funding Agency and Grant Number |
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| Corresponding Author |
Jun-Min Yu, Department of Pain Treatment, The Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Qingdao 266000, Shandong Province, China. longalley2011@qdu.edu.cn |
| Key Words |
Immune checkpoint inhibitors; Digestive system neoplasms; Programmed cell death 1 receptor; Umbrella review; Meta-analysis |
| Core Tip |
In this umbrella review, we selected 59 reviews and meta-analyses of programmed cell death protein 1/programmed death ligand 1 (immune checkpoint inhibitors) to find out how effective are these new therapeutics in five cancers of the digestive system. We applied AMSTAR-1 (a measurement tool to assess systematic reviews) and grading of recommendations assessment, development, and evaluation to map out the hierarchy of evidence. In our review, immune checkpoint inhibitors have activity in gastric and esophageal cancers, but more than half of the outcomes we covered rest on low- or very-low-certainty evidence. |
| Citation |
Yu JJ, Zhu L, Li XP, Wang LP, Meng FG, Sui WX, Feng XJ, Sui YY, Leng P, Yu JM. Efficacy and safety of immune checkpoint inhibitors in the treatment of digestive system cancers: An umbrella review. World J Gastrointest Oncol 2026; In press
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| PDF |
124379-in-press.pdf
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Received |
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2026-06-15 07:04 |
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Peer-Review Started |
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2026-06-15 07:04 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-07-07 05:59 |
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Revised |
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2026-07-31 16:50 |
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Publication Fee Transferred |
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2026-08-21 10:27 |
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Second Decision by Editor |
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2026-10-14 05:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-10-14 08:38 |
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Articles in Press |
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2026-10-14 08:38 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
