| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Core symptoms and network analysis in patients with gastroesophageal reflux disease based on body mass index
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yi-Qing Mao, Zhong-Yu Li, Zhi-Kun Wang, Hai-Yan Bai, Bo-Lin Li, Feng-Liang Tian, Shun-Yong He, Li-Jian Liu, Xiao-Yan Huang, Lei Zhu, Hui Che, Dan-Ming Wu, Yang-Yang Zhang, Lan-Shuo Hu, Wen-Hao Zhang, Bo Li and Ying-Pan Zhao |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| General Program of National Natural Science Foundation of China |
No. 82374435 |
| Training Program for Outstanding Young Scientific and Techno-logical Talents (Innovative Category), and China Academy of Chinese Medical Sciences |
No. ZZ13-YQ-011 |
| Beijing Nova Program |
No. 20250484815 |
|
| Corresponding Author |
Ying-Pan Zhao, Chief Physician, Institute of Digestive Diseases, Xiyuan Hospital of China Academy of Chinese Medical Sciences, No. 1 Xiyuan Cao Chang Road, Haidian District, Beijing 100091, China. xyyy_zyp@163.com |
| Key Words |
Gastroesophageal reflux disease; Body mass index; Symptom network; Core symptoms; Network analysis; Overweight |
| Core Tip |
This first symptom network analysis of gastroesophageal reflux disease stratified by body mass index (BMI) reveals that depression and bloating are core symptoms irrespective of BMI. In overweight patients (BMI ≥ 25 kg/m²), anxiety, shortness of breath, and abdominal distension emerge as particularly influential. These findings provide novel, BMI-differentiated targets for symptom management in gastroesophageal reflux disease. |
| Citation |
Mao YQ, Li ZY, Wang ZK, Bai HY, Li BL, Tian FL, He SY, Liu LJ, Huang XY, Zhu L, Che H, Wu DM, Zhang YY, Hu LS, Zhang WH, Li B, Zhao YP. Core symptoms and network analysis in patients with gastroesophageal reflux disease based on body mass index. World J Gastroenterol 2026; In press
|
