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Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 124479
Country Greece
Category Oncology
Manuscript Type Review
Article Title Sarcopenia as a prognostic factor in gastric cancer patients undergoing gastrectomy: Implications for postoperative and long-term outcomes
Manuscript Source Invited Manuscript
All Author List Kalliopi Vakalou, Alexandra Dimaki, Lydia Lazaridou, Konstantinos Elefterios Koumarelas, Dimitrios Schizas and Grigorios Christodoulidis
Funding Agency and Grant Number
Corresponding Author Grigorios Christodoulidis, Department of General Surgery, University Hospital of Larissa, Mezourlo, Larissa 41110, Thessalia, Greece. gregsurg@yahoo.gr
Key Words Gastric cancer; Gastrectomy; Sarcopenia; Body composition; Skeletal muscle index; Postoperative complications; Overall survival; Sarcopenic obesity
Core Tip Sarcopenia is increasingly recognized as a clinically important predictor of outcome in patients undergoing gastrectomy due to gastric cancer. Reduced skeletal mass, muscle quality and functional performance contribute to postoperative morbidity and long-term prognosis. Systemic inflammation and adipose tissue distribution also play a significant role. This review highlights the growing need for multidimensional assessment models that incorporate computed tomography-derived body composition markers as well as functional tests and markers of nutritional-inflammatory activity. Incorporating sarcopenia into preoperative risk stratification may improve patient selection. Finally, it may guide perioperative optimization and support more personalized surgical and oncological management.
Citation Vakalou K, Dimaki A, Lazaridou L, Koumarelas KE, Schizas D, Christodoulidis G. Sarcopenia as a prognostic factor in gastric cancer patients undergoing gastrectomy: Implications for postoperative and long-term outcomes. World J Gastrointest Surg 2026; In press
Received
2026-06-16 03:24
Peer-Review Started
2026-06-16 03:24
First Decision by Editorial Office Director
Return for Revision
2026-07-01 01:56
Revised
2026-07-14 06:12
Publication Fee Transferred
Second Decision by Editor
2026-07-24 03:17
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-27 07:38
Articles in Press
2026-07-27 07:38
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-9366 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com