Publication Name	World Journal of Translational Medicine
Manuscript ID	124522
Country	Cote d'Ivoire

Category	Critical Care Medicine
Manuscript Type	Case Report
Article Title	Fatal hemorrhagic transformation after ischemic stroke in a child with sickle cell disease SS: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Sêtondji Emmanuel Raymond Ahouangansi, Adelin Sahya Ouohi, Loes Koffi, Affoua Mouroufié Kossonou, Koffi Isidore Kouamé, Cyrille Toure, Yao Vianney Bédié, Koffi Manassé Kakou, Etienne Spah N’dah, Kadidja Koné, Stéphane Charles Evrard Adingra, Konaté Aboudramane and Yikpé Denis Ayé
Funding Agency and Grant Number
Corresponding Author	Sêtondji Emmanuel Raymond Ahouangansi, Assistant Professor, Department of Anesthesiology and Critical Care, Faculty of Medical Sciences, Félix Houphouët-Boigny University, Abidjan 01 BP V 34, 01, Cote d'Ivoire. aemmaray15@gmail.com
Key Words	Anemia; sickle cell; Stroke; Malaria; Falciparum; Child; Africa South of the Sahara; Secondary prevention; Hemorrhagic transformation; Case report
Core Tip	This case highlights the fatal consequences of absent secondary stroke prevention in a child with sickle cell disease homozygous SS (SCD-SS). An 8-year-old girl who survived an initial ischemic stroke subsequently developed a fatal hemorrhagic stroke in the setting of Plasmodium falciparum malaria, without having received secondary preventive care. In sub-Saharan Africa, limited access to transcranial Doppler screening and exchange transfusion programs continues to place children with SCD-SS at high risk of recurrent cerebrovascular events. This report underscores the urgent need to strengthen early screening and secondary stroke prevention strategies in resource-limited settings.
Citation	Ahouangansi SER, Ouohi A, Koffi L, Kossonou AM, Kouamé KI, Toure WC, Bédié YV, Kakou KM, N’dah ES, Koné K, Adingra SCE, Aboudramane K, Ayé YD. Fatal hemorrhagic transformation after ischemic stroke in a child with sickle cell disease SS: A case report. World J Transl Med 2026; In press

Received	2026-06-18 03:19
Peer-Review Started	2026-06-18 03:19
First Decision by Editorial Office Director
Return for Revision	2026-07-26 22:41
Revised	2026-08-12 13:27
Publication Fee Transferred
Second Decision by Editor	2026-10-10 03:25
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-10-10 09:02
Articles in Press	2026-10-10 09:02
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-6132 (online)
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