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9/22/2026 9:49:48 AM | Browse: 86 | Download: 8
Publication Name World Journal of Gastroenterology
Manuscript ID 124778
DOI 10.3748/wjg.124778
Country China
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Multidimensional magnetic resonance imaging nomogram for noninvasive stratification of mismatch repair status in rectal cancer: A multicenter study
Manuscript Source Unsolicited Manuscript
All Author List Hong-Xia Zhong, Jian-Xin Zhang, Li-Juan Wan, Wei Rao, Wen-Hua Wang, Jian-Feng Zhang, Hong-Mei Zhang and Qing Zhao
Funding Agency and Grant Number
Funding Agency Grant Number
the CAMS Innovation Fund for Medical Sciences (CIFMS) 2025-I2M-C&T-B-063
Fundamental Research Program of Shanxi Province 202403021211143
Corresponding Author Qing Zhao, Department of Diagnostic Radiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Panjiayuannanli, Beijing 100021, China. zq_pumc@163.com
Key Words Rectal cancer; Mismatch repair deficiency; Magnetic resonance imaging; Radiomics; Fractal dimension
Core Tip Deficient mismatch repair status determines immunotherapy eligibility for rectal cancer patients but relies on pathological detection of endoscopic biopsy specimens which are sometimes unobtainable; we constructed and externally validated a pretreatment magnetic resonance imaging radiomic prediction model incorporating fractal dimension features via a 1:2 matched retrospective case-control design, which may facilitate noninvasive pretreatment identification of deficient mismatch repair tumors and reduce missed screening of patients eligible for immune checkpoint inhibitor therapy.
Citation Zhong HX, Zhang JX, Wan LJ, Rao W, Wang WH, Zhang JF, Zhang HM, Zhao Q. Multidimensional magnetic resonance imaging nomogram for noninvasive stratification of mismatch repair status in rectal cancer: A multicenter study. World J Gastroenterol 2026; In press
PDF 124778-in-press.pdf
Received
2026-06-24 09:29
Peer-Review Started
2026-06-24 09:29
First Decision by Editorial Office Director
Return for Revision
2026-07-22 04:01
Revised
2026-07-31 13:53
Publication Fee Transferred
2026-08-19 13:55
Second Decision by Editor
2026-09-22 03:46
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-09-22 09:49
Articles in Press
2026-09-22 09:49
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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