BPG is committed to discovery and dissemination of knowledge
Articles in Press
9/24/2026 8:49:23 AM | Browse: 8 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 124812
DOI 10.3748/wjg.124812
Country China
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Epidemiology, genetics, clinical characteristics, and dietary risk factors of familial celiac disease in China: A cross-sectional study
Manuscript Source Unsolicited Manuscript
All Author List Sheng-Long Xue, Tian Shi, Dan-Ni Chen, Tuomalisi Ainiwaer, Jin-Jin Xie, Gulisitan Abula, Jia-Li Hu, Maimaitireyimu Ayinuer and Feng Gao
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China No. 82460117
Department of Human Resources and Social Security of Xinjiang Uygur Autonomous Region, Xinjiang Strategic Talent Training Program No. XJRC-2025-RS-PY-TX-043
Corresponding Author Feng Gao, Honorary Research Fellow, MD, PhD, Professor, Professor Emerita, Research Fellow, Researcher, Department of Gastroenterology, People’s Hospital of Xinjiang Uygur Autonomous Region, No. 91 Tianchi Road, Tianshan District, Urumqi 830001, Xinjiang Uygur Autonomous Region, China. xjgf@sina.com
Key Words Celiac disease; China; Epidemiology; HLA-DQ2/8; Gastrointestinal symptoms; Dietary habits
Core Tip This first systematic survey of 29 Chinese celiac disease (CeD) families revealed a prevalence of 15.2% among first-degree relatives and 12.1% among second-degree relatives. Carriers of HLA-DQ2.5/DQ2.2 and DQ2.5/DQ2.5 genotypes exhibited the highest risk. Among individuals with comparable genetic risk, higher wheat and milk tea consumption were associated with increased CeD risk, suggesting that dietary factors may modulate disease expression beyond genetic susceptibility.
Citation Xue SL, Shi T, Chen DN, Ainiwaer T, Xie JJ, Abula G, Hu JL, Ayinuer M, Gao F. Epidemiology, genetics, clinical characteristics, and dietary risk factors of familial celiac disease in China: A cross-sectional study. World J Gastroenterol 2026; In press
PDF 124812-in-press.pdf
Received
2026-06-29 08:31
Peer-Review Started
2026-06-29 08:31
First Decision by Editorial Office Director
Return for Revision
2026-07-27 06:09
Revised
2026-08-06 13:41
Publication Fee Transferred
2026-08-14 13:00
Second Decision by Editor
2026-09-24 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-09-24 08:49
Articles in Press
2026-09-24 08:49
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com