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10/8/2026 8:23:19 AM | Browse: 5 | Download: 0
| Category |
Psychiatry |
| Manuscript Type |
Retrospective Study |
| Article Title |
Acupuncture for fatigue and sleep disturbance in patients with mild-to-moderate depression: A retrospective propensity score-matched cohort study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yi Wang, Ittipalanukul Penpat, Zheng Wu, Xiao-Xiao Jin, Le-Ping Huang, Zhi-Hai Hu and Qun Lu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Hongkou District’s Third Round “Strengthen and Excel National Medicine” Three-Year Action Plan (2026-2028), Sheng-Style Acupuncture School Heritage Construction Project |
HKGYQYXM-2026-55 |
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| Corresponding Author |
Zhi-Hai Hu, Department of Acupuncture and Moxibustion, Shanghai Traditional Chinese Medicine-Integrated Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, No. 230 Baoding Road, Hongkou District, Shanghai 200082, China. keyanzhenjiu@126.com |
| Key Words |
Acupuncture; Depression; Fatigue; Sleep disturbance; Hypothalamic-pituitary-adrenal axis; NLRP3 inflammasome |
| Core Tip |
This retrospective propensity score-matched cohort study found that adding acupuncture to escitalopram was associated with greater improvements in depression, fatigue, and sleep quality than escitalopram alone. The parallel changes in hypothalamic-pituitary-adrenal hormones, NLRP3-related markers, brain-derived neurotrophic factor, and P300 generate hypotheses for future research but should be regarded as exploratory associative findings. The main clinical implication is that acupuncture may be a feasible adjunct for patients with persistent fatigue and insomnia despite pharmacotherapy, pending confirmation in randomized trials. |
| Citation |
Wang Y, Penpat I, Wu Z, Jin XX, Huang LP, Hu ZH, Lu Q. Acupuncture for fatigue and sleep disturbance in patients with mild-to-moderate depression: A retrospective propensity score-matched cohort study. World J Psychiatry 2026; In press
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Received |
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2026-07-24 10:42 |
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Peer-Review Started |
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2026-07-24 10:42 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-08-14 08:12 |
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Revised |
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2026-08-25 02:26 |
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Publication Fee Transferred |
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2026-09-11 09:10 |
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Second Decision by Editor |
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2026-10-08 07:09 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-10-08 08:23 |
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Articles in Press |
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2026-10-08 08:23 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
