Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	124885
DOI	10.4251/wjgo.124885
Country	China

Category	Surgery
Manuscript Type	Retrospective Cohort Study
Article Title	Dynamic gut microbiota and serum metabolite changes post-gastrectomy affect nutrient absorption in gastric cancer patients
Manuscript Source	Unsolicited Manuscript
All Author List	Min-Xia Li, Hui-Chun Chen, Lei-Lei Yu and Pei-Sheng Jin
Funding Agency and Grant Number
Corresponding Author	Pei-Sheng Jin, Chief Physician, Department of Gastroenterology, Ruian People’s Hospital, No. 108 Wansong Road, Rui’an 325200, Zhejiang Province, China. jps0001@163.com
Key Words	Gastric cancer; Gastrectomy; Gut microbiota; Serum metabolites; Bile acids; Malnutrition; Longitudinal study
Core Tip	This prospective longitudinal study compared the dynamic effects of distal gastrectomy, total gastrectomy, and endoscopic submucosal dissection on gut microbiota and serum metabolites in gastric cancer patients. A surgery-extent-dependent gradient of dysbiosis and bile acid metabolic disturbances was observed. endoscopic submucosal dissection preserved gastric integrity, thereby maintaining microbial homeostasis. Early postoperative Streptococcus overgrowth may serve as an early warning sign of long-term malnutrition.
Citation	Li MX, Chen HC, Yu LL, Jin PS. Dynamic gut microbiota and serum metabolite changes post-gastrectomy affect nutrient absorption in gastric cancer patients. World J Gastrointest Oncol 2026; In press DOI: https://doi.org/10.4251/wjgo.124885
PDF	124885-in-press.pdf

Received	2026-07-10 11:14
Peer-Review Started	2026-07-10 11:14
First Decision by Editorial Office Director
Return for Revision	2026-07-28 02:08
Revised	2026-08-04 08:20
Publication Fee Transferred	2026-08-07 07:47
Second Decision by Editor	2026-09-14 03:05
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-09-15 09:38
Articles in Press	2026-09-15 09:38
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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