Publication Name	World Journal of Transplantation
Manuscript ID	124920
DOI	10.5500/wjt.124920
Country	United Arab Emirates

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Minireviews
Article Title	Donor heart preservation fluids: Conventional solutions, emerging strategies, and current evidence
Manuscript Source	Invited Manuscript
All Author List	Salman Pervaiz Butt, Mitesh Badiwala, Rhea Anand, Salman Abdulaziz, Irfan Rasheed, Nadya Al Matrooshi and Gopal Bhatnagar
Funding Agency and Grant Number
Corresponding Author	Salman Pervaiz Butt, Assistant Professor, Manager, Perfusion, Heart Vascular and Thoracic Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi 112412, United Arab Emirates. butts2@ccad.ae
Key Words	Heart transplantation; Organ preservation; Ischemia-reperfusion injury; Static cold storage; University of Wisconsin solution; Celsior; Histidine-tryptophan-ketoglutarate solution; Machine perfusion; Donation after circulatory death
Core Tip	Preservation-fluid selection cannot be separated from donor pathway, temperature control, perfusion, transport, and graft assessment. Direct comparisons among University of Wisconsin, Celsior, and histidine-tryptophan-ketoglutarate are mainly observational, heterogeneous, and confounded; no fluid has established universal superiority. Randomized trials support specific perfusion strategies in defined donation after brain death or donation after circulatory death contexts, but these results should not be extrapolated to isolated fluid choice. Preservation is best interpreted as an integrated pathway that also accounts for access, training, regulation, and cost.
Citation	Butt SP, Badiwala M, Anand R, Abdulaziz S, Rasheed I, Al Matrooshi N, Bhatnagar G. Donor heart preservation fluids: Conventional solutions, emerging strategies, and current evidence. World J Transplant 2026; In press DOI: https://doi.org/10.5500/wjt.124920
PDF	124920-in-press.pdf

Received	2026-07-02 02:52
Peer-Review Started	2026-07-02 02:53
First Decision by Editorial Office Director
Return for Revision	2026-08-20 16:28
Revised	2026-08-28 21:58
Publication Fee Transferred
Second Decision by Editor	2026-10-16 03:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-10-16 09:15
Articles in Press	2026-10-16 09:15
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3230 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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