Publication Name	World Journal of Clinical Cases
Manuscript ID	125054
DOI	10.12998/wjcc.125054
Country	United States

Category	Orthopedics
Manuscript Type	Retrospective Cohort Study
Article Title	Obesity and postoperative opioid utilization after total knee arthroplasty: A propensity-matched analysis
Manuscript Source	Invited Manuscript
All Author List	Kevin A Wu, Eric Mai, Christopher S Warburton, Suraj Dhanjani, Ankit Choudhury, Francesca Docters, Laurel Wong, Anjali Prabhat, Marium Raza, Omri Maayan, Junho Song, Michael Shatkin, Calin S Moucha and Brett L Hayden
Funding Agency and Grant Number
Corresponding Author	Kevin A Wu, MD, Researcher, Department of Orthopedics, Icahn School of Medicine at Mount Sinai, 1 Gustave L Levy Pl, New York, NY 10029, United States. kevin.wu2@mountsinai.org
Key Words	Total knee arthroplasty; Obesity; Body mass index, Opioid prescribing; Propensity score matching; Postoperative pain; Opioid stewardship
Core Tip	This large propensity-matched national cohort study examined how body mass index (BMI) relates to opioid prescribing after primary total knee arthroplasty (TKA) in opioid-naive patients. Patients with obesity (BMI 30 kg/m² or greater) had a modestly higher likelihood of receiving postoperative opioid prescriptions, but greater obesity severity, including morbid obesity (BMI 40 kg/m² or greater), was not associated with more prescriptions. BMI alone may therefore be a limited predictor of postoperative opioid prescribing after TKA, and individualized evaluation of psychosocial and pain-related risk factors may better guide opioid stewardship.
Citation	Wu KA, Mai E, Warburton CS, Dhanjani S, Choudhury A, Docters F, Wong L, Prabhat A, Raza M, Maayan O, Song J, Shatkin M, Moucha CS, Hayden BL. Obesity and postoperative opioid utilization after total knee arthroplasty: A propensity-matched analysis. World J Clin Cases 2026; In press DOI: https://doi.org/10.12998/wjcc.125054
PDF	125054-in-press.pdf

Received	2026-07-07 06:24
Peer-Review Started	2026-07-07 06:24
First Decision by Editorial Office Director
Return for Revision	2026-07-16 02:27
Revised	2026-07-31 01:46
Publication Fee Transferred
Second Decision by Editor	2026-08-20 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-08-20 09:17
Articles in Press	2026-08-20 09:17
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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