Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	125329
DOI	10.4251/wjgo.125329
Country	India

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Beyond dysbiosis: Reframing microbiome-associated diseases from taxonomy to functional and ecological models
Manuscript Source	Invited Manuscript
All Author List	Devi Lal, Himani Pandey and Sunny H Wong
Funding Agency and Grant Number
Corresponding Author	Devi Lal, Assistant Professor, PhD, Department of Zoology, Ramjas College, University of Delhi, University Enclave, Delhi 110007, Delhi, India. devilal@ramjas.du.ac.in
Key Words	Gut microbiome; Dysbiosis; Host-microbiome interactions; Metabolomics; Fecal microbiota transplantation; Microbial ecology; Precision medicine
Core Tip	Dysbiosis is a key concept in modern medicine and has been linked to the pathophysiology of many gastrointestinal diseases. The dysbiosis concept remains poorly defined, and its scientific utility is limited by five major limitations. In this review, we propose five complementary dimensions to traditional dysbiosis and construct an integrative hierarchical model linking host characteristics and microbial community structure and function to disease outcomes.
Citation	Lal D, Pandey H, Wong SH. Beyond dysbiosis: Reframing microbiome-associated diseases from taxonomy to functional and ecological models. World J Gastrointest Oncol 2026; In press DOI: https://doi.org/10.4251/wjgo.125329
PDF	125329-in-press.pdf

Received	2026-07-06 05:56
Peer-Review Started	2026-07-06 05:56
First Decision by Editorial Office Director
Return for Revision	2026-08-07 09:33
Revised	2026-08-12 13:15
Publication Fee Transferred
Second Decision by Editor	2026-11-02 02:19
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-11-04 10:26
Articles in Press	2026-11-04 10:26
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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