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Articles in Press
10/20/2026 9:41:15 AM | Browse: 8 | Download: 0
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Distinct reflux mechanisms in patients with different pulmonary phenotypes of extraesophageal reflux
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ruo-Xi Zhang, Yang Chen, Ju-Hong Shi, Zhi-Feng Wang, Wen-Yan Zhu, Min Peng, Gui-Jun Fei, Xiu-Cai Fang, Ai-Ming Yang and Xiao-Qing Li |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Noncommunicable Chronic Diseases-National Science and Technology Major Project |
No. 2025ZD0552407 |
| National Key Research and Development Program of China |
No. 2022YFC3602103 |
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| Corresponding Author |
Xiao-Qing Li, MD, Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan, Dongcheng District, Beijing 100730, China. lixiaoqing20060417@126.com |
| Key Words |
Extraesophageal reflux; Pulmonary phenotype; Reflux characteristics; Parenchymal disorder; Airway disorder; Interstitial disorder |
| Core Tip |
This cross-sectional study found that the different pulmonary phenotypes of extraesophageal reflux have distinct reflux and esophageal motility profiles. Airway disorders were mostly characterized by increased distal reflux, whereas parenchymal disorders were associated with proximal mucosal impairment. Interstitial pulmonary involvement was characterized by prominent esophageal dysmotility and impaired distal mucosal integrity. These results suggest that the different phenotypes of extraesophageal reflux have distinct underlying pathophysiological mechanisms. |
| Citation |
Zhang RX, Chen Y, Shi JH, Wang ZF, Zhu WY, Peng M, Fei GJ, Fang XC, Yang AM, Li XQ. Distinct reflux mechanisms in patients with different pulmonary phenotypes of extraesophageal reflux. World J Gastroenterol 2026; In press
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| PDF |
125368-in-press.pdf
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Received |
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2026-07-06 07:55 |
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Peer-Review Started |
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2026-07-06 07:55 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-08-11 03:42 |
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Revised |
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2026-08-23 15:32 |
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Publication Fee Transferred |
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2026-09-16 10:38 |
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Second Decision by Editor |
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2026-10-20 02:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-10-20 09:41 |
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Articles in Press |
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2026-10-20 09:41 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
