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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 125500
DOI 10.4251/wjgo.125500
Country China
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Comparative evaluation of questionnaire-based risk assessment and fecal immunochemical test for colorectal cancer screening
Manuscript Source Unsolicited Manuscript
All Author List Hui-Li Kang, Li Hua, Si-Jing Rong, Kai-Xing Zhu, Hai-Bo Yu, Ying-Ru Liang, Qin Fang, Hai-Qing Liang, Jiao-Xiang Zhang and Gui-Yuan Han
Funding Agency and Grant Number
Funding Agency Grant Number
the Guangzhou Municipal Government and the Haizhu District Government, Guangzhou, China, and Shenzhen High-Level Hospital Construction Fund GSP-QNPY-B2025011
Corresponding Author Gui-Yuan Han, Researcher, Shenzhen Clinical Research Center for Cardiovascular Disease, Fuwai Shenzhen Hospital, Chinese Academy of Medical Sciences, No. 12 Langshan Road, Xili Street, Nanshan District, Shenzhen 518000, Guangdong Province, China. han.guiyuan@qq.com
Key Words Colorectal cancer screening; Fecal immunochemical test; Colonoscopy compliance; Questionnaire-based risk assessment; Community-based screening
Core Tip The high-risk factor questionnaire (HRFQ) and fecal immunochemical test (FIT) are widely used in colorectal cancer (CRC) screening. Using data from a large community-based screening program, factors associated with screening positivity, colonoscopy compliance, and diagnostic outcomes were compared across the two screening approaches. FIT-positive individuals showed higher colonoscopy compliance and a greater yield of target lesions (advanced adenomas or early-stage CRC), whereas the HRFQ identified a broader high-risk population. These findings highlight potentially complementary roles of HRFQ and FIT in community-based CRC screening and provide insights into the two screening approaches for different populations.
Citation Kang HL, Hua L, Rong SJ, Zhu KX, Yu HB, Liang YR, Fang Q, Liang HQ, Zhang JX, Han GY. Comparative evaluation of questionnaire-based risk assessment and fecal immunochemical test for colorectal cancer screening. World J Gastrointest Oncol 2026; In press
PDF 125500-in-press.pdf
Received
2026-07-14 07:00
Peer-Review Started
2026-07-14 07:00
First Decision by Editorial Office Director
Return for Revision
2026-08-07 01:46
Revised
2026-09-04 07:22
Publication Fee Transferred
2026-10-21 06:32
Second Decision by Editor
2026-11-05 03:30
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-11-05 08:02
Articles in Press
2026-11-05 08:02
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5204 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
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