Publication Name	World Journal of Stem Cells
Manuscript ID	125599
DOI	10.4252/wjsc.125599
Country	China

Category	Oncology
Manuscript Type	Minireviews
Article Title	RNA-centered mechanisms sustaining self-renewal in hepatocellular carcinoma stem cells: Effector dosage, protein output and regulatory deployment
Manuscript Source	Invited Manuscript
All Author List	Yi Deng and Long Yan
Funding Agency and Grant Number
Corresponding Author	Yi Deng, MD, Department of Oncology, The Second Xiangya Hospital of Central South University, No. 139 Renmin Middle Road, Changsha 410011, Hunan Province, China. dengyi@csu.edu.cn
Key Words	Hepatocellular carcinoma; Cancer stem cells; RNA-centered regulation; Self-renewal; Post-transcriptional control
Core Tip	Here, we examine how RNA molecules and RNA-processing machineries maintain functional self-renewal by controlling self-renewal effectors. Rather than cataloging RNA classes, we organize the evidence by molecular operation. RNA mechanisms first tune effector dosage and availability through transcript repression, stabilization, export, translational access and protein turnover.
Citation	Deng Y, Yan L. RNA-centered mechanisms sustaining self-renewal in hepatocellular carcinoma stem cells: Effector dosage, protein output and regulatory deployment. World J Stem Cells 2026; In press DOI: https://doi.org/10.4252/wjsc.125599
PDF	125599-in-press.pdf

Received	2026-07-14 09:01
Peer-Review Started	2026-07-14 09:02
First Decision by Editorial Office Director
Return for Revision	2026-08-10 01:44
Revised	2026-08-12 13:21
Publication Fee Transferred
Second Decision by Editor	2026-09-10 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-09-11 09:28
Articles in Press	2026-09-11 09:28
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-0210 (online)
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