Publication Name	World Journal of Gastroenterology
Manuscript ID	125700
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Development and validation of a clinical-radiological model for predicting myocardial injury in moderately severe and severe acute pancreatitis
Manuscript Source	Unsolicited Manuscript
All Author List	Ju Zhang, Rong Peng, Shu-Jiao Li, Lin-Xia Wang, Chun-Rong Tu, Xu-Rui Liu, Xiao-Ming Zhang and Tian-Wu Chen
Funding Agency and Grant Number
Corresponding Author	Tian-Wu Chen, Key Laboratory of Intelligent Processing and Applications of Medical Imaging Big Data, Chongqing Municipal Health Commission, Department of Radiology, The Second Affiliated Hospital of Chongqing Medical University, No. 74 Linjiang Road, Yuzhong, Chongqing 400010, China. chentw@hospital.cqmu.edu.cn
Key Words	Acute pancreatitis; Myocardial injury; Predictive model; Computed tomography; Magnetic resonance imaging; External validation
Core Tip	Reliable tools for predicting myocardial injury among patients with moderately severe acute pancreatitis and severe acute pancreatitis are lacking. Computed tomography/magnetic resonance severity index score and clinical variables including age, blood urea nitrogen, and D-dimer level were identified as independent predictors of myocardial injury. We developed and externally validated a clinical-radiological predictive model integrating these routinely available clinical variables with the computed tomography severity index/magnetic resonance severity index score. The resulting model demonstrated robust predictive performance across independent cohorts. Myocardial injury was independently associated with in-hospital mortality. This model may facilitate timely identification of high-risk patients, closer cardiovascular monitoring, and risk-informed clinical management.
Citation	Zhang J, Peng R, Li SJ, Wang LX, Tu CR, Liu XR, Zhang XM, Chen TW. Development and validation of a clinical-radiological model for predicting myocardial injury in moderately severe and severe acute pancreatitis. World J Gastroenterol 2026; In press

Received	2026-07-15 07:09
Peer-Review Started	2026-07-15 07:09
First Decision by Editorial Office Director
Return for Revision	2026-07-27 06:11
Revised	2026-08-10 03:32
Publication Fee Transferred	2026-08-19 08:53
Second Decision by Editor	2026-09-17 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-09-17 09:31
Articles in Press	2026-09-17 09:31
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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