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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 125732
DOI 10.4251/wjgo.125732
Country China
Category Oncology
Manuscript Type Retrospective Study
Article Title Neoadjuvant chemotherapy vs chemoradiotherapy for locally advanced gastric cancer: A propensity score-matched study
Manuscript Source Unsolicited Manuscript
All Author List Yi-Fan Wang, Xia-Xi Qiao, Quan-Ming Liu, Yong-Wen Song, Hui Fang, Bo Chen, Ning-Ning Lu, Shu-Nan Qi, Hao Jing, Shu-Lian Wang, Ye-Xiong Li, Jing Jin, Yuan Tang and Ning Li
Funding Agency and Grant Number
Funding Agency Grant Number
National Cancer Center Climbing Fund No. NCC202414002
Corresponding Author Ning Li, Full Professor, Department of Radiation Oncology, Shanxi Province Cancer Hospital Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences Cancer Hospital Affiliated to Shanxi Medical University Cancer Hospital Affiliated to Shanxi Medical University, No. 3 Zhigongxin Street, Taiyuan 030013, Shanxi Province, China. lee_ak@163.com
Key Words Gastric adenocarcinoma; Neoadjuvant therapy; Chemotherapy; Chemoradiotherapy; Postoperative complications
Core Tip Using propensity score matching, this study compared neoadjuvant chemoradiotherapy (nCRT) with neoadjuvant chemotherapy in locally advanced gastric cancer (LAGC), focusing on postoperative complications and pathological outcomes. No statistically significant difference in postoperative complications was observed between the two groups, whereas nCRT was associated with significantly higher pathological complete response and favorable tumor regression rates (1-2). These findings suggest that nCRT is a feasible neoadjuvant strategy for LAGC and may provide improved pathological responses, warranting further prospective evaluation.
Citation Wang YF, Qiao XX, Liu QM, Song YW, Fang H, Chen B, Lu NN, Qi SN, Jing H, Wang SL, Li YX, Jin J, Tang Y, Li N. Neoadjuvant chemotherapy vs chemoradiotherapy for locally advanced gastric cancer: A propensity score-matched study. World J Gastrointest Oncol 2026; In press
Received
2026-07-15 07:09
Peer-Review Started
2026-07-15 07:10
First Decision by Editorial Office Director
Return for Revision
2026-08-25 14:25
Revised
2026-09-07 15:01
Publication Fee Transferred
2026-09-25 03:16
Second Decision by Editor
2026-10-30 07:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-10-30 10:22
Articles in Press
2026-10-30 10:22
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5204 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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