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Articles in Press
10/10/2026 9:12:44 AM | Browse: 12 | Download: 0
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Robot-assisted massage is associated with improved duodenal barrier-related outcomes in a rabbit model of functional dyspepsia
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yi-Chao Zhang, Wu-Xia Yang, Jia-Lu Hou, Zi-Xuan Wang, Zhi-Kai Huang, Hong-Lin Li, Ming-Zheng Kek, De-Rong Lin, Ru-Hao Wu and Ji-Hong Wang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
No. 82474667 |
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| Corresponding Author |
Ji-Hong Wang, Full Professor, PhD, Clinical Medical College of Acupuncture-Moxibustion and Rehabilitation, Guangzhou University of Chinese Medicine, No. 232 Waihuan East Road, Panyu District, Guangzhou 510006, Guangdong Province, China. 13622882891@163.com |
| Key Words |
Functional dyspepsia; Robot-assisted massage; Gastrointestinal motility; Rabbit model; Duodenal epithelial barrier; Tight junctions; Mechanical pressure |
| Core Tip |
This study standardized robot-assisted massage pressure and showed a pressure-response pattern that was not monotonic across the three tested pressure levels in a functional dyspepsia-like rabbit model. Medium-pressure produced the most consistent improvements in body weight, food intake, gastrointestinal motility, duodenal structural integrity, inflammatory and barrier-related markers, and epithelial junction-associated proteins, whereas light-pressure produced less consistent improvements and heavy-pressure showed no consistent benefit, with unfavorable changes in several outcomes. These responses were accompanied by changes in myosin light chain kinase, phosphorylated myosin light chain, E-cadherin, and junctional proteins; however, these expression changes do not establish causal mediation through the myosin light chain kinase/phosphorylated myosin light chain/E-cadherin pathway. |
| Citation |
Zhang YC, Yang WX, Hou JL, Wang ZX, Huang ZK, Li HL, Kek MZ, Lin DR, Wu RH, Wang JH. Robot-assisted massage is associated with improved duodenal barrier-related outcomes in a rabbit model of functional dyspepsia. World J Gastroenterol 2026; In press
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Received |
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2026-07-17 07:17 |
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Peer-Review Started |
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2026-07-17 07:17 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-08-04 06:31 |
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Revised |
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2026-08-17 08:47 |
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Publication Fee Transferred |
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2026-09-08 07:17 |
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Second Decision by Editor |
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2026-10-10 03:25 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-10-10 09:12 |
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Articles in Press |
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2026-10-10 09:12 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
