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Publication Name World Journal of Psychiatry
Manuscript ID 125848
Country China
Category Psychiatry
Manuscript Type Observational Study
Article Title Reproductive cycle-related mood episode history as a clinical characteristic for symptom severity in women with mood disorders
Manuscript Source Unsolicited Manuscript
All Author List Xin-Yu Hu, Xu-Zhen Liu, Xiao-Fang Shang, Hua-Bing Song, Yan Zheng, Jia-Ming Lin, Jun-Jun Liu and Jing Sun
Funding Agency and Grant Number
Funding Agency Grant Number
Jiangsu Province High-Level Hospital Construction Project Su Wei Yi Zheng [2023] 53
Corresponding Author Jing Sun, Associate Professor, Chief Physician, Head, Department of Psychiatry, Nanjing Medical University Affiliated Brain Hospital, No. 264 Guangzhou Road, Gulou District, Nanjing 210029, Jiangsu Province, China. jingsun2007@163.com
Key Words Mood disorders; Reproductive cycle; Mood episode history; Hormone sensitivity
Core Tip By integrating mood episode histories across three major reproductive windows (premenstrual, perinatal, and perimenopausal periods), this study provides a lifespan perspective on reproductive cycle-related mood vulnerability in women with mood disorders. A history of reproductive cycle-related mood episodes was associated with greater depressive and anxiety symptom severity, as well as greater childhood emotional neglect and negative life event impact. Importantly, symptom differences were primarily observed between women without and those with any positive reproductive window history, whereas additional affected windows were not associated with further increases in symptom severity.
Citation Hu XY, Liu XZ, Shang XF, Song HB, Zheng Y, Lin JM, Liu JJ, Sun J. Reproductive cycle-related mood episode history as a clinical characteristic for symptom severity in women with mood disorders. World J Psychiatry 2026; In press
Received
2026-07-20 09:01
Peer-Review Started
2026-07-20 09:01
First Decision by Editorial Office Director
Return for Revision
2026-08-28 01:29
Revised
2026-09-07 13:15
Publication Fee Transferred
2026-09-30 10:15
Second Decision by Editor
2026-10-23 02:59
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-10-23 09:09
Articles in Press
2026-10-23 09:09
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-3206 (online)
Open Access Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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