Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	125918
DOI	10.4253/wjge.125918
Country	Italy

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Endoscopic ultrasound-guided ablation of small pancreatic neuroendocrine neoplasms: Bridging the gap between surveillance and surgery
Manuscript Source	Invited Manuscript
All Author List	Sara Massironi, Giuseppe Dell'Anna, Paolo Biamonte, Francesca Bernardi and Silvio Danese
Funding Agency and Grant Number
Corresponding Author	Sara Massironi, Associate Professor, Department of Medicine and Surgery, Vita-Salute San Raffaele University, Via Olgettina 56, Milan 20132, Lombardy, Italy. sara.massironi@libero.it
Key Words	Pancreatic neuroendocrine neoplasms; Endoscopic ultrasound; Radiofrequency ablation; Ethanol ablation; Insulinoma; Pancreas-preserving treatment; Therapeutic endoscopy
Core Tip	Small pancreatic neuroendocrine neoplasms pose a therapeutic dilemma because surveillance may expose selected patients to tumor progression and psychological burden, whereas pancreatic surgery carries substantial morbidity. Endoscopic ultrasound-guided ethanol injection and radiofrequency ablation offer a pancreas-preserving intermediate strategy. This review summarizes current techniques, clinical outcomes, safety considerations, and proposed selection criteria, emphasizing that endoscopic ultrasound-guided ablation should currently be reserved for carefully selected patients treated in expert multidisciplinary centers.
Citation	Massironi S, Dell'Anna G, Biamonte P, Bernardi F, Danese S. Endoscopic ultrasound-guided ablation of small pancreatic neuroendocrine neoplasms: Bridging the gap between surveillance and surgery. World J Gastrointest Endosc 2026; In press DOI: https://doi.org/10.4253/wjge.125918
PDF	125918-in-press.pdf

Received	2026-07-21 06:26
Peer-Review Started	2026-07-21 06:44
First Decision by Editorial Office Director
Return for Revision	2026-07-24 08:07
Revised	2026-07-29 07:05
Publication Fee Transferred
Second Decision by Editor	2026-09-04 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-09-04 10:25
Articles in Press	2026-09-04 10:25
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5190 (online)
Open Access	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com