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Publication Name World Journal of Cardiology
Manuscript ID 126179
Country China
Category Cardiac & Cardiovascular Systems
Manuscript Type Minireviews
Article Title Prognostic value and limitations of the pericoronary fat attenuation index: A narrative review
Manuscript Source Invited Manuscript
All Author List Guo-Ping Ma, Xiang-Jie Wu and Chong-Fu Jia
Funding Agency and Grant Number
Corresponding Author Chong-Fu Jia, PhD, Professor, The Department of Cardiovascular Radiology, The First Affiliated Hospital of Dalian Medical University, Zhong Shan Road, Dalian 116011, Liaoning Province, China. wzx1128@163.com
Key Words Coronary computed tomographic angiography; Pericoronary fat attenuation index; Prognosis; Major adverse cardiovascular events; Progression
Core Tip The pericoronary fat attenuation index (FAI) can reflect coronary inflammation by quantifying perivascular fat attenuation. Baseline FAI has shown potential in plaque assessment and major adverse cardiovascular events prediction. Still, its utility is limited by confounders such as age, sex, body mass index, tube voltage, and reconstruction algorithms, causing heterogeneous cutoffs (-76.3 HU to -67.4 HU). Dynamic changes in FAI derived from serial coronary computed tomographic angiography reflect temporal inflammatory activity and help account for baseline inter-individual variability, thereby providing enhanced insights into cardiovascular risk over single-timepoint FAI assessment.
Citation Ma GP, Wu XJ, Jia CF. Prognostic value and limitations of the pericoronary fat attenuation index: A narrative review. World J Cardiol 2026; In press
Received
2026-07-28 08:13
Peer-Review Started
2026-08-05 06:24
First Decision by Editorial Office Director
Return for Revision
2026-09-01 07:09
Revised
2026-09-14 09:00
Publication Fee Transferred
Second Decision by Editor
2026-10-23 02:59
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-10-23 09:12
Articles in Press
2026-10-23 09:12
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1949-8462 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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