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Publication Name World Journal of Gastroenterology
Manuscript ID 126483
DOI 10.3748/wjg.126483
Country China
Category Gastroenterology & Hepatology
Manuscript Type Correspondence
Article Title Letter to the Editor: Sex-specific differences in 5-aminosalicylic acid therapy for ulcerative colitis: Is it still the case in smokers?
Manuscript Source Unsolicited Manuscript
All Author List Jing Xu, En-Ming Zhang and Jing-Bo Wang
Funding Agency and Grant Number
Corresponding Author Jing-Bo Wang, MD, Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China. wangjingbo201001@163.com
Key Words Ulcerative colitis; 5-aminosalicylic acid therapy; Sex; Smoking; Disease duration
Core Tip Although Liu’s study delivered clinically relevant evidence of sex-based response difference to 5-aminosalicylic acid in ulcerative colitis, two major methodological limitations may weaken its robustness and generalizability. The conclusions drawn from this study could not be directly extended to patients who smoke, and external validation in smokers is needed. The authors should also provide an explicit definition of disease duration and conduct supplementary analyses to elucidate the effect of longer disease duration on outcomes.
Citation Xu J, Zhang EM, Wang JB. Letter to the Editor: Sex-specific differences in 5-aminosalicylic acid therapy for ulcerative colitis: Is it still the case in smokers? World J Gastroenterol 2026; In press
PDF 126483-in-press.pdf
Received
2026-08-14 02:40
Peer-Review Started
2026-08-14 02:40
First Decision by Editorial Office Director
Return for Revision
2026-09-02 08:20
Revised
2026-09-13 12:10
Publication Fee Transferred
Second Decision by Editor
2026-11-05 02:47
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-11-05 09:05
Articles in Press
2026-11-05 09:05
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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