Publication Name	World Journal of Critical Care Medicine
Manuscript ID	126670
DOI	10.5492/wjccm.126670
Country	United States

Category	Critical Care Medicine
Manuscript Type	Translational Research
Article Title	Antithrombotic status and intracerebral hemorrhage in the setting of extracorporeal membrane oxygenation
Manuscript Source	Invited Manuscript
All Author List	Amir Mahdi Ghafarian, Muazz Wajahath, Mohammad Ghafarian, Zoya Syed, Abbasali Badami, Khaled Saleh, Faddi Saleh Velez, Adnan I Qureshi, Denise Battaglini and Andrea Loggini
Funding Agency and Grant Number
Corresponding Author	Andrea Loggini, MD, Brain and Spine Institute, Southern Illinois Healthcare, 405 W Jackson Street, Carbondale, IL 62901, United States. andrea.loggini@sih.net
Key Words	Intracerebral hemorrhage; Extracorporeal membrane oxygenation; Anticoagulation; Antiplatelet therapy; Antithrombotic therapy; Mortality; Retrospective cohort study; Observational study
Core Tip	In this retrospective study of 2213 observations of nontraumatic intracerebral hemorrhage in the setting of extracorporeal membrane oxygenation, recorded antithrombotic status at the index date was not associated with 30-day mortality in any of four timing windows. In unadjusted analyses, dual therapy was associated with higher rates of cardiac arrest and blood transfusion in early windows. Antithrombotic status functioned as a marker of illness severity rather than a modifiable exposure; these hypothesis-generating findings support configuration-aware prospective studies.
Citation	Ghafarian AM, Wajahath M, Ghafarian M, Syed Z, Badami A, Saleh K, Saleh Velez F, Qureshi AI, Battaglini D, Loggini A. Antithrombotic status and intracerebral hemorrhage in the setting of extracorporeal membrane oxygenation. World J Crit Care Med 2026; In press DOI: https://doi.org/10.5492/wjccm.126670
PDF	126670-in-press.pdf

Received	2026-08-10 01:55
Peer-Review Started	2026-08-11 08:16
First Decision by Editorial Office Director
Return for Revision	2026-09-14 08:08
Revised	2026-09-15 19:30
Publication Fee Transferred
Second Decision by Editor	2026-11-12 06:01
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-11-12 10:02
Articles in Press	2026-11-12 10:02
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3141(online)
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