Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	127023
DOI	10.4253/wjge.127023
Country	Pakistan

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	From pixels to prevention: Can artificial intelligence transform the endoscopic management of colorectal neoplasia?
Manuscript Source	Invited Manuscript
All Author List	Muhammad Abdul Haseeb Khan, Abdullah Saeed, Hafiz Hanzala Tufail, Bakhtiar Ameer Tahir and Ehtezaz Khan Ali Zai
Funding Agency and Grant Number
Corresponding Author	Muhammad Abdul Haseeb Khan, Researcher, Department of Medicine, Ayub Medical College, Main Mansehra Road, Abbottabad 22010, Khyber Pakhtunkhwa, Pakistan. drhaseebkhan11@gmail.com
Key Words	Artificial intelligence; Colonoscopy; Computer-aided detection; Computer-aided characterization; Colorectal neoplasia
Core Tip	Artificial intelligence is rapidly expanding the capabilities of colorectal endoscopy, but technological performance does not necessarily translate into clinical benefit. Computer-aided detection improves adenoma detection and reduces adenoma miss rates, whereas evidence for computer-aided characterization, lesion quantification, therapeutic assessment, and surveillance remains less mature. This review proposes a “pixels-to-prevention” framework spanning image interpretation, detection, characterization, clinical decision-making, therapy, surveillance, and prevention. The central challenge is to establish whether artificial intelligence-assisted endoscopy ultimately improves patient-important outcomes, including colorectal cancer incidence, mortality, complications, and healthcare utilization.
Citation	Khan MAH, Saeed A, Tufail HH, Tahir BA, Zai EKA. From pixels to prevention: Can artificial intelligence transform the endoscopic management of colorectal neoplasia? World J Gastrointest Endosc 2026; In press DOI: https://doi.org/10.4253/wjge.127023
PDF	127023-in-press.pdf

Received	2026-08-19 03:30
Peer-Review Started	2026-08-19 03:30
First Decision by Editorial Office Director
Return for Revision	2026-09-04 06:22
Revised	2026-09-04 17:25
Publication Fee Transferred
Second Decision by Editor	2026-10-15 03:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-10-16 09:04
Articles in Press	2026-10-16 09:04
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5190 (online)
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