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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 127041
DOI 10.4251/wjgo.127041
Country China
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title From prediction to intervention: Translating machine learning risk models into clinical decision support for gastric cancer surgery
Manuscript Source Invited Manuscript
All Author List Wen-Li Wang, Jun Jiang and Hai-Qiang Wang
Funding Agency and Grant Number
Funding Agency Grant Number
Weifang City Science and Technology Development Plan (Medical Category) 2023YX057
Weifang Traditional Chinese Medicine Scientific Research Program WFZYY2025-3-018
Corresponding Author Jun Jiang, Operating Room, Affiliated Hospital of Shandong Second Medical University (Clinical Medical College), No. 2428 Yuhe Road, Kuiwen District, Weifang 261000, Shandong Province, China. fyjiangjun@sdsmu.edu.cn
Key Words Gastric cancer; Gastrectomy; Artificial intelligence; Clinical decision support systems; Machine learning; Postoperative complications; Anastomotic leakage; Implementation science
Core Tip Machine learning risk models for gastric cancer surgery increasingly predict complications with high reported discrimination, yet few reach the bedside. This narrative review synthesizes the translation gap across technical, clinical, organizational/regulatory, and ethical dimensions, clearly separating direct gastric-cancer evidence from indirect evidence from other settings, and proposes a conceptual five-stage framework — from clinical-need definition and intrinsically explainable design, through prospective multicenter validation with decision curve analysis and workflow-embedded user-centered prototyping, to post-deployment monitoring with continuous learning. Gradient-boosted models for delayed wound healing exemplify this gap, and a Danish colorectal cancer artificial intelligence implementation provides a benchmark; the field must shift from model-centric area under the receiver operating characteristic curve metrics to patient-centric, continuously evaluated decision support.
Citation Wang WL, Jiang J, Wang HQ. From prediction to intervention: Translating machine learning risk models into clinical decision support for gastric cancer surgery. World J Gastrointest Oncol 2026; In press
PDF 127041-in-press.pdf
Received
2026-08-20 07:25
Peer-Review Started
2026-08-20 07:26
First Decision by Editorial Office Director
Return for Revision
2026-09-29 00:38
Revised
2026-10-08 03:30
Publication Fee Transferred
Second Decision by Editor
2026-11-12 05:53
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-11-12 10:05
Articles in Press
2026-11-12 10:05
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ISSN 1948-5204 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
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