| Category |
Surgery |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Association of one-year postoperative patient-reported outcomes with recurrence and survival in stage I non-small-cell lung cancer
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Giovanni Leuzzi, Beatrice Cosentino, Federica Sabia, Ugo Pastorino, Cecilia Pompili, Wei Dai, Francesco Guerrera, Elena Prisciandaro, Filippo Lococo, Michele Ferrari, Luigi Rolli, Alessandro Pardolesi, Alessia Stanzi, Matteo Calderoni, Clarissa Uslenghi, Daniele Lorenzini, Alessandra Fabbri, Claudia Proto, Giuseppe Lo Russo, Arsela Prelaj, Alfonso Marchianò, Giorgio Greco and Piergiorgio Solli |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Giovanni Leuzzi, Consultant, MD, Senior Researcher, Division of Thoracic Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Giacomo Venezian 1, Milan 20133, Lombardy, Italy. giovanni.leuzzi@istitutotumori.mi.it |
| Key Words |
Non-small-cell lung cancer; Patient-reported outcomes; Health-related quality of life; Recurrence; Overall survival; Survivorship |
| Core Tip |
This landmark study evaluated whether patient-reported outcomes assessed 1 year after curative-intent resection for stage I non-small-cell lung cancer were associated with subsequent recurrence and survival. Among 232 patients alive and recurrence-free at the landmark, global health status, fatigue, and dyspnea showed distinct associations with recurrence, while dyspnea was associated with overall survival and fatigue showed a borderline association in the primary model. These findings suggest that postoperative patient-reported outcomes may provide complementary prognostic information during long-term survivorship. |
| Citation |
Leuzzi G, Cosentino B, Sabia F, Pastorino U, Pompili C, Dai W, Guerrera F, Prisciandaro E, Lococo F, Ferrari M, Rolli L, Pardolesi A, Stanzi A, Calderoni M, Uslenghi C, Lorenzini D, Fabbri A, Proto C, Lo Russo G, Prelaj A, Marchiano A, Greco G, Solli P. Association of one-year postoperative patient-reported outcomes with recurrence and survival in stage I non-small-cell lung cancer. World J Clin Oncol 2026; In press
|
| PDF |
127553-in-press.pdf
|
