Publication Name	World Journal of Gastroenterology
Manuscript ID	30518
Country	United States

Category	Gastroenterology & Hepatology
Manuscript Type	Evidence-Based Medicine
Article Title	Substantial hepatic necrosis is prognostic in fulminant liver failure
Manuscript Source	Invited Manuscript
All Author List	Paul Ndekwe, Marwan S Ghabril, Yong Zang, Steven A Mann, Oscar W Cummings and Jingmei Lin
Funding Agency and Grant Number
Corresponding Author	Jingmei Lin, MD, PhD, Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, 350 West 11th Street, Indianapolis, IN 46202, United States. jinglin@iupui.edu
Key Words	Submassive necrosis; Massive necrosis; Fulminant liver failure; Liver transplantation; Biopsy; Histopathology
Core Tip	Fulminant liver failure is clinically characterized by an abrupt onset of jaundice and liver dysfunction with subsequent development of encephalopathy and coagulopathy in patients with or without preexisting liver disease. Liver biopsy may play a role in predicting patient survival, and may also potentially play a role in optimizing the utilization of resources in the setting of fulminant liver failure.
Citation	Ndekwe P, Ghabril MS, Zang Y, Mann SA, Cummings OW, Lin J. Substantial hepatic necrosis is prognostic in fulminant liver failure. World J Gastroenterol 2017; 23(23): 4303-4310

Received	2016-10-07 15:32
Peer-Review Started	2016-10-10 10:27
To Make the First Decision	2016-12-19 09:50
Return for Revision	2016-12-20 20:39
Revised	2017-03-21 06:05
Second Decision	2017-05-15 02:53
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-05-19 08:28
Articles in Press	2017-05-19 08:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-06-10 10:48

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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