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Publication Name World Journal of Gastrointestinal Endoscopy
Manuscript ID 32759
Country United States
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Correlation of abnormal histology with endoscopic findings among mycophenolate mofetil treated patients
Manuscript Source Invited Manuscript
All Author List Mitchell A Izower, Merajur Rahman, Ernesto P Molmenti, Madhu C Bhaskaran, Viren G Amin, Sundas Khan and Keith Sultan
Funding Agency and Grant Number
Corresponding Author Merajur Rahman, MD, Division of Gastroenterology, Department of Medicine, North Shore University Hospital, 300 Community Drive, Manhasset, NY 11030, United States. rmerajur@nshs.edu
Key Words Mycophenolate mofetil; Colitis; Colonoscopy; Diarrhea
Core Tip Gastrointestinal complaints are common among patients using mycophenolate mofetil (MMF). Little information exits to guide an effective endoscopic workup in this population. A retrospective review of all patients prescribed mycophenolate within 6 mo of an endoscopic procedure was performed. Our results demonstrate a high rate of left sided disease and microscopic findings without gross mucosal abnormalities among patients using mycophenolate. A broader definition of MMF-colonopathy may be appropriate, with a majority of our abnormal histology falling outside of the more narrowly defined MMF-colitis category. Our findings suggest sigmoidoscopy with random biopsies may be an appropriate initial evaluation.
Citation Izower MA, Rahman M, Molmenti EP, Bhaskaran MC, Amin VG, Khan S, Sultan K. Correlation of abnormal histology with endoscopic findings among mycophenolate mofetil treated patients. World J Gastrointest Endosc 2017; 9(8): 405-410
Received
2017-01-22 10:16
Peer-Review Started
2017-01-22 17:18
To Make the First Decision
2017-03-28 17:40
Return for Revision
2017-04-01 11:51
Revised
2017-04-23 22:14
Second Decision
2017-05-17 09:33
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-05-24 01:48
Articles in Press
2017-05-24 01:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-07-17 07:54
ISSN 1948-5190 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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