Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	33069
Country	Hungary

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Analysis of risk factors - especially different types of plexitis - for postoperative relapse in Crohn’s disease
Manuscript Source	Invited Manuscript
All Author List	Ágnes Milassin, Anita Sejben, László Tiszlavicz, Zita Reisz, György Lázár, Mónika Szűcs, Renáta Bor, Anita Bálint, Mariann Rutka, Zoltán Szepes, Ferenc Nagy, Klaudia Farkas and Tamás Molnár
Funding Agency and Grant Number
Corresponding Author	Ágnes Milassin, MD, First Department of Internal Medicine, University of Szeged, 6720 Szeged, Korányi fasor 8-10, Hungary. milassin.agnes.eszter@med.u-szeged.hu
Key Words	Submucosal plexitis; Postoperative recur­rence; Crohn’s disease; Stricturing disease behavior; Isolated ileal disease
Core Tip	This is a retrospective study to evaluate the presence of submucosal and myenteric plexitis and its role in predicting postoperative recurrence (POR) in Crohn’s disease. Demographic data, smoking habits, previous resection, treatment before and after surgery, and histological findings were evaluated as possible predictors of POR. We found that the severity of sub­muco­sal plexitis was a predictor of the need for second surgery. Other predictors of POR were female gender, stricturing disease behavior, and isolated ileal localization. Our results did not confirm the hypothesis that myenteric plexitis can be predictive of postoperative relapse.
Citation	Milassin Á, Sejben A, Tiszlavicz L, Reisz Z, Lázár G, Szűcs M, Bor R, Bálint A, Rutka M, Szepes Z, Nagy F, Farkas K, Molnár T. Analysis of risk factors - especially different types of plexitis - for postoperative relapse in Crohn’s disease. World J Gastrointest Surg 2017; 9(7): 167-173

Received	2017-02-04 15:14
Peer-Review Started	2017-02-06 21:48
To Make the First Decision	2017-03-13 17:46
Return for Revision	2017-03-17 11:33
Revised	2017-04-25 13:56
Second Decision	2017-05-17 09:35
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-05-24 01:52
Articles in Press	2017-05-24 01:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-07-13 08:49

ISSN	1948-9366 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com