Publication Name	World Journal of Gastroenterology
Manuscript ID	33562
Country	South Korea

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Risk factors for metachronous gastric carcinoma development after endoscopic resection of gastric dysplasia: Retrospective, single-center study
Manuscript Source	Unsolicited Manuscript
All Author List	Hee Seok Moon, Gee Young Yun, Ju Seok Kim, Hyuk Soo Eun, Sun Hyung Kang, Jae Kyu Sung, Hyun Yong Jeong and Kyu-Sang Song
Funding Agency and Grant Number
Corresponding Author	Jae Kyu Sung, MD, PhD, Department of Internal Medicine, Chungnam National University School of Medicine, 282 Munhwa-ro, Jung-gu, Daejeon 35015, South Korea. jksung69@cnuh.co.kr
Key Words	Gastric dysplasia; Neoplasms; Second primary; Endoscopic mucosal resection; Stomach neoplasms
Core Tip	Gastric dysplasia is considered a premalignant lesion that can become malignant. Thus, endoscopic resection is preferred not only for the removal of these lesions but also for exact diagnosis. In our study, we investigated the relationship between the occurrence of synchronous and metachronous lesions after endoscopic treatment of gastric dysplasia and various clinical factors during the follow-up period. The incidence rates of synchronous and metachronous neoplasms after endoscopic resection of gastric dysplasia were 12.1% and 13.8%, respectively. In the multivariate analysis, age of < 60 years and intestinal metaplasia were independent risk factors of synchronous neoplasm. For metachronous neoplasm, especially metachronous gastric adenocarcinoma, independent risk factors were male sex, intestinal metaplasia, and high-grade dysplasia.
Citation	Moon HS, Yun GY, Kim JS, Eun HS, Kang SH, Sung JK, Jeong HY, Song KS. Risk factors for metachronous gastric carcinoma development after endoscopic resection of gastric dysplasia: Retrospective, single-center study. World J Gastroenterol 2017; 23(24): 4407-4415

Received	2017-02-17 09:20
Peer-Review Started	2017-02-17 14:57
To Make the First Decision	2017-03-16 13:18
Return for Revision	2017-03-22 09:30
Revised	2017-04-04 04:40
Second Decision	2017-05-18 03:48
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-05-19 08:00
Articles in Press	2017-05-19 08:00
Publication Fee Transferred	2017-05-22 04:11
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-06-16 02:56

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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