Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	34010
Country	United States

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Declining use of combination infliximab and immunomodulator for inflammatory bowel disease in the community setting
Manuscript Source	Unsolicited Manuscript
All Author List	Joshua C Berkowitz, Joanna Stein-Fishbein, Sundas Khan, Richard Furie and Keith S Sultan
Funding Agency and Grant Number
Corresponding Author	Keith S Sultan, MD, Assistant Professor, Hofstra Northwell School of Medicine, 300 Community Dr., Manhasset, NY 11030, United States. ksultan@northwell.edu
Key Words	Crohn’s disease; Ulcerative colitis; Infliximab; Azathioprine; Inflammatory bowel disease
Core Tip	In our 13 year experience at a community hospital infusion center, approximately 26% of inflammatory bowel disease patients receiving infliximab infusions received concomitant immunomodulator therapy. This is comparable to rates of combination therapy (CT) at major tertiary referral centers. However, there was a trend of decreased utilization of CT over the study period, even following the publication of SONIC. This suggests a need for further study to define the population with the most favorable risk-benefit ratio from CT, as well as the need for more direct guidelines from major societies.
Citation	Berkowitz JC, Stein-Fishbein J, Khan S, Furie R, Sultan KS. Declining use of combination infliximab and immunomodulator for inflammatory bowel disease in the community setting. World J Gastrointest Pharmacol Ther 2018; 9(1): 8-13

Received	2017-03-21 09:13
Peer-Review Started	2017-03-23 16:51
To Make the First Decision	2017-05-03 14:52
Return for Revision	2017-05-08 20:10
Revised	2017-06-12 14:19
Second Decision	2017-11-06 01:29
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-11-10 05:31
Articles in Press	2017-11-10 05:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-01-25 09:28

ISSN	2150-5349 (online)
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