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9/13/2017 7:37:40 PM | Browse: 239 | Download: 437
Publication Name World Journal of Clinical Cases
Manuscript ID 34766
Country/Territory Japan
Category Pathology
Manuscript Type Case Report
Article Title Case of gastric neuroendocrine carcinoma showing an interesting tumorigenic pathway
Manuscript Source Unsolicited Manuscript
All Author List Noriyuki Uesugi, Ryo Sugimoto, Makoto Eizuka, Yasuko Fujita, Mitsumasa Osakabe, Keisuke Koeda, Takashi Kosaka, Shunichi Yanai, Kazuyuki Ishida, Akira Sasaki, Takayuki Matsumoto and Tamotsu Sugai
Funding Agency and Grant Number
Corresponding Author Tamotsu Sugai, MD, Professor, Department of Molecular Diagnostic Pathology, Iwate Medical University, 19-1, Morioka 020-8505, Japan. tsugai@iwate-med.ac.jp
Key Words Stomach; Neuroendocrine tumor G2; Neuroendocrine tumor G3; Neuroendocrine carcinoma
Core Tip Gastric neuroendocrine carcninoma (NEC) is typically generated by dedifferentiation of adenocarcinoma cells to endocrine cells. However, we experienced a case of gastric NEC possibly generated from the neuroendocrine tumor (NET) component. The present case demonstrated an unconventional carcinogenic pathway in neuroendocrine tumorigenesis. In addition, we analyzed allelic imbalance (AI) in NET and NEC components and provided important insights into neuroendocrine carcinogenesis.
Citation Uesugi N, Sugimoto R, Eizuka M, Fujita Y, Osakabe M, Koeda K, Kosaka T, Yanai S, Ishida K, Sasaki A, Matsumoto T, Sugai T. Case of gastric neuroendocrine carcinoma showing an interesting tumorigenic pathway. World J Clin Cases 2017; In press
Received
2017-06-01 01:23
Peer-Review Started
2017-06-03 06:46
To Make the First Decision
2017-06-27 01:44
Return for Revision
2017-06-28 11:10
Revised
2017-07-13 05:54
Second Decision
2017-08-30 04:34
Accepted by Journal Editor-in-Chief
2017-08-30 05:29
Accepted by Company Editor-in-Chief
2017-09-13 19:37
Articles in Press
2017-09-13 19:37
Publication Fee Transferred
2017-10-29 06:13
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-11-10 01:16
ISSN 2307-8960 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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