Publication Name	World Journal of Gastroenterology
Manuscript ID	35124
Country	Italy

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Are liver nested stromal epithelial tumors always low aggressive?
Manuscript Source	Unsolicited Manuscript
All Author List	Tania Meletani, Luca Cantini, Andrea Lanese, Daniele Nicolini, Alessia Cimadamore, Andrea Agostini, Giulia Ricci, Stefania Antognoli, Alessandra Mandolesi, Maria Guido, Rita Alaggio, Gian Marco Giuseppetti, Marina Scarpelli, Marco Vivarelli and Rossana Berardi
Funding Agency and Grant Number
Corresponding Author	Rossana Berardi, MD, Professor, Head of Department of Medical Oncology, Director of the Postgraduate School of Medical Oncology, Director of “Genetic Cancer” Center, Deputy Director of Department of Clinical and Molecular Science, University Hospital and Polytechnic University, via conca 71, Ancona 60126, Italy. r.berardi@univpm.it
Key Words	Nested stromal epithelial tumor; Liver; Rare; Chemotherapy; Aggressive; Metastatic
Core Tip	Nested stromal-epithelial tumor (NSET) of the liver is a very rare type of cancer, few cases have been reported in the world. Most of the literature described a low tendency of relapse, the majority of the reported cases have been treated with surgery, obtaining a long survival outcome. Our patient developed a more aggressive disease, which relapsed soon after surgery, and progressed after first line chemotherapy. We aimed to update the literature about NEST; especially in patients with either metastatic or recurrent disease, for whom no standard treatment is now available.
Citation	Meletani T, Cantini L, Lanese A, Nicolini D, Cimadamore A, Agostini A, Ricci G, Antognoli S, Mandolesi A, Guido M, Alaggio R, Giuseppetti GM, Scarpelli M, Vivarelli M, Berardi R. Are liver nested stromal epithelial tumors always low aggressive? World J Gastroenterol 2017; 23(46): 8248-8255

Received	2017-06-21 01:27
Peer-Review Started	2017-06-22 02:23
To Make the First Decision	2017-07-13 05:26
Return for Revision	2017-07-18 10:05
Revised	2017-07-27 16:05
Second Decision	2017-08-21 04:30
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-08-25 14:25
Articles in Press	2017-08-25 14:25
Publication Fee Transferred	2017-11-03 06:02
Edit the Manuscript by Language Editor	2017-11-15 13:41
Typeset the Manuscript	2017-11-20 09:12

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com