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9/19/2017 8:46:33 PM | Browse: 200 | Download: 528
Publication Name World Journal of Gastroenterology
Manuscript ID 35255
Country/Territory China
Category Oncology
Manuscript Type Basic Study
Article Title Relationship between autophagy and perineural invasion, clinicopathological features, and prognosis in pancreatic cancer
Manuscript Source Unsolicited Manuscript
All Author List Yan-Hui Yang, Jiang-Bo Liu, Yang Gui, Liang-Liang Lei and Shui-Jun Zhang
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China U1504815
Corresponding Author Shui-Jun Zhang, MD, PhD, Professor, Surgeon, Department of Hepatobiliary and Pancreatic Surgery, the First Affiliated Hospital of Zhengzhou University, Jianshe East Road, Zhengzhou 450052, China. zhangshuijun@zzu.edu.cn
Key Words Pancreatic cancer; Perineural invasion; Autophagy; Clinical pathological features; Prognosis
Core Tip The relationship between autophagy and perineural invasion (PNI) was explored for the first time in pancreatic cancer. Pancreatic cancer PNI is related to microtubule-associated protein 1A/1B-light chain 3 (LC3) expression-determined autophagy. PNI and LC3 expression were independent prognostic factors in pancreatic cancer. There might be a special association between autophagy and PNI, contributing to pancreatic cancer progression. This study might provide a new insight for the mechanism of PNI in pancreatic cancer.
Citation Yang YH, Liu JB, Gui Y, Lei LL, Zhang SJ. Relationship between autophagy and perineural invasion, clinicopathological features, and prognosis in pancreatic cancer. World J Gastroenterol 2017; 23(40): 7232-7241
Received
2017-08-17 00:22
Peer-Review Started
2017-08-17 09:52
To Make the First Decision
2017-08-30 00:13
Return for Revision
2017-08-30 09:23
Revised
2017-09-13 16:52
Second Decision
2017-09-14 07:32
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-09-19 20:46
Articles in Press
2017-09-19 20:46
Publication Fee Transferred
2017-09-28 10:03
Edit the Manuscript by Language Editor
2017-10-11 14:03
Typeset the Manuscript
2017-10-23 03:17
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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