Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	35509
Country	United Kingdom

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Mediastinal node staging by positron emission tomography-computed tomography and selective endoscopic ultrasound with fine needle aspiration for patients with upper gastrointestinal cancer: Results from a regional centre
Manuscript Source	Invited Manuscript
All Author List	Chris Harrington, Lyn Smith, Jennifer Bisland, Elisabet López González, Neil Jamieson, Stuart Paterson and Adrian John Stanley
Funding Agency and Grant Number
Corresponding Author	Adrian John Stanley, BM BCh, FRCP (C), MD, Associate Professor, Doctor, Glasgow Royal Infirmary, Castle Street, Walton Building, Glasgow G4 0SF, United Kingdom. adrian.stanley@ggc.scot.nhs.uk
Key Words	Oesophageal cancer; Oesophago-gastric cancer staging; Endoscopic ultrasound; Positron emission tomography-computed tomography; Mediastinal nodes
Core Tip	We have found that positron emission tomography-computed tomography (PET-CT) in the setting of upper GI cancer has a high sensitivity and negative predictive value, but has poor specificity and positive predictive value for the detection of malignant mediastinal lymph nodes. This could lead to many patients being over-staged by PET-CT alone. The use of endoscopic ultrasound-guided fine-needle aspiration of mediastinal nodes results in more patients being offered radical therapy.
Citation	Harrington CG, Smith L, Bisland J, Lopez Gonzalez E, Jamieson N, Paterson S, Stanley AJ. Mediastinal node staging by positron emission tomography-computed tomography and selective endoscopic ultrasound with fine needle aspiration for patients with upper gastrointestinal cancer: Results from a regional centre. World J Gastrointest Endosc 2018; 10(1): 37-44

Received	2017-07-27 01:34
Peer-Review Started	2017-07-28 02:15
To Make the First Decision	2017-09-07 06:44
Return for Revision	2017-09-11 04:04
Revised	2017-09-25 12:56
Second Decision	2017-11-14 11:11
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-11-20 04:32
Articles in Press	2017-11-20 04:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-01-07 11:17

ISSN	1948-5190 (online)
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