Publication Name	World Journal of Gastroenterology
Manuscript ID	35685
Country	United States

Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Chronic opioids in gastroparesis: Relationship with gastrointestinal symptoms, healthcare utilization and employment
Manuscript Source	Unsolicited Manuscript
All Author List	Asad Jehangir and Henry P Parkman
Funding Agency and Grant Number
Corresponding Author	Henry P Parkman, MD, Professor, Department of Gastroenterology, Temple University Hospital, 3401 North Broad Street, Philadelphia, PA 19140, United States. henry.parkman@tuhs.temple.edu
Key Words	Opioid; Gastroparesis; Symptoms; Hospitalizations; Employment
Core Tip	Chronic opioid use can cause gastrointestinal side effects and negatively influence the quality of life. The impact of chronic opioid use on symptoms, healthcare utilization, and employment of gastroparesis patients is not well studied. In our study, gastroparesis patients on chronic scheduled opioids had more severe gastrointestinal symptoms, less work productivity and more frequent hospitalizations compared to gastroparesis patients without opioid use. Whether opioid use is to treat a higher symptom severity from gastroparesis, or the opioid use worsens symptoms requires further study.
Citation	Jehangir A, Parkman HP. Chronic opioids in gastroparesis: Relationship with gastrointestinal symptoms, healthcare utilization and employment. World J Gastroenterol 2017; 23(40): 7310-7320

Received	2017-07-31 03:18
Peer-Review Started	2017-08-01 10:22
To Make the First Decision	2017-08-30 02:54
Return for Revision	2017-08-31 07:32
Revised	2017-09-08 23:27
Second Decision	2017-09-15 01:59
Accepted by Journal Editor-in-Chief	2017-09-15 16:02
Accepted by Company Editor-in-Chief	2017-09-19 20:52
Articles in Press	2017-09-19 20:52
Publication Fee Transferred	2017-10-18 03:35
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-10-23 03:19

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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