Publication Name	World Journal of Hepatology
Manuscript ID	36310
Country	Russia

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Multipotent stromal cells stimulate liver regeneration by influencing the macrophage polarization in rat
Manuscript Source	Invited Manuscript
All Author List	Andrey Elchaninov, Timur Fatkhudinov, Natalia Usman, Irina Arutyunyan, Andrey Makarov, Anastasia Lokhonina, Irina Eremina, Viktor Surovtsev, Dmitry Goldshtein, Galina Bolshakova, Valeria Glinkina and Gennady Sukhikh
Funding Agency and Grant Number	Funding Agency Grant Number Russian Science Foundation 17-15-01419
Corresponding Author	Timur Fatkhudinov, DSc, MD, PhD, Academic Research, Laboratory of Regenerative Medicine, National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I.Kulakov of Ministry of Healthcare of Russian Federation, 4 Oparina Street, Moscow 117997, Russian Federation, Moscow 117997, Russia. tfat@yandex.ru
Key Words	Liver; Regeneration; Multipotent stromal cells; Macrophages
Core Tip	Umbilical cord-derived multipotent stromal cells stimulate reparative processes within the liver after subtotal resection (removal of 80% of the organ mass). Multipotent stromal cells stimulate hepatocyte proliferation in rats after subtotal resection and favor polarization of macrophages to M2 phenotype. The transplanted MSCs do not differentiate into any of the liver cell types under these conditions.
Citation	Elchaninov A, Fatkhudinov T, Usman N, Arutyunyan I, Makarov A, Lokhonina A, Eremina I, Surovtsev V, Goldshtein D, Bolshakova G, Glinkina V, Sukhikh G. Multipotent stromal cells stimulate liver regeneration by influencing the macrophage polarization in rat. World J Hepatol 2018; 10(2): 287-296

Received	2017-09-19 00:26
Peer-Review Started	2017-09-20 09:23
To Make the First Decision	2017-10-30 06:57
Return for Revision	2017-10-31 06:38
Revised	2017-10-31 14:00
Second Decision	2017-11-23 07:57
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2018-02-06 01:43
Articles in Press	2018-02-06 01:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-03-01 11:53

ISSN	1948-5182 (online)
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