Publication Name	World Journal of Gastroenterology
Manuscript ID	36498
Country	China

Category	Microbiology
Manuscript Type	Review
Article Title	Relationship between intestinal microbiota and ulcerative colitis: Mechanisms and clinical application of probiotics and fecal microbiota transplantation
Manuscript Source	Unsolicited Manuscript
All Author List	Zhao-Hua Shen, Chang-Xin Zhu, Yong-Sheng Quan, Zhen-Yu Yang, shuai Wu, Wei-Wei Luo, Bei Tan and Xiao-Yan Wang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81670504 National Natural Science Foundation of China 81472287 New Xiangya Talent Project of the Third Xiangya Hospital of Central South University 20150308
Corresponding Author	Xiao-Yan Wang, MD, PhD, Professor, Department of Gastroenterology, Third Xiangya Hospital, Central South University, 138 Tongzipo Road, Yuelu District, Changsha 410013, Hunan Province, China. wangxiaoyan2913@126.com
Key Words	fecal microbiota transplantation; Intestinal microbiota; ulcerative colitis; probiotics; mechanism; clinical application
Core Tip	As we all know, genetic factors, host immune system disorders, intestinal microbiota dysbiosis, and environmental factors contribute to the pathogenesis of ulcerative colitis (UC). In this review, we explore the mechanism and clinical application of intestinal microbiota such as probiotics and fecal microbiota transplantation in UC so that we can use these tools to cure more diseases. Enteric microbiota leads to new therapeutic strategies for UC.
Citation	Shen ZH, Zhu CX, Quan YS, Yang ZY, Wu S, Luo WW, Tan B, Wang XY. Relationship between intestinal microbiota and ulcerative colitis: Mechanisms and clinical application of probiotics and fecal microbiota transplantation. World J Gastroenterol 2018; 24(1): 5-14

Received	2017-10-03 06:35
Peer-Review Started	2017-10-03 14:52
To Make the First Decision	2017-10-18 06:50
Return for Revision	2017-10-19 09:09
Revised	2017-11-07 23:45
Second Decision	2017-11-21 12:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2017-11-21 18:39
Articles in Press	2017-11-21 18:39
Publication Fee Transferred
Edit the Manuscript by Language Editor	2017-12-02 00:06
Typeset the Manuscript	2018-01-05 00:55

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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