Publication Name	World Journal of Hepatology
Manuscript ID	36923
Country	Romania

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Metabolomics: From liver chiromancy to personalized precision medicine in advanced chronic liver disease
Manuscript Source	Invited Manuscript
All Author List	Bogdan Procopet, Petra Fischer, Oana Farcau and Horia Stefanescu
Funding Agency and Grant Number	Funding Agency Grant Number UEFISCDI, Romania PN-II-RU-TE-2014-4-0709 UEFISCDI, Romania PN-II-RU-TE-2014-4-0356
Corresponding Author	Horia Stefanescu, MD, MSc, PhD, Doctor, Staff Physician, Hepatology Unit, Regional Institute of Gastroenterology and Hepatology, str Croitorilor nr 19-21, Cluj 400162, Cluj, Romania. horia.stefanescu@irgh.ro
Key Words	Metabolomics; Biomarker; Prediction; Advanced chronic liver disease; Decompensation; Alcoholic hepatitis; Hepatocellular carcinoma
Core Tip	Currently there is a lack of accurate biomarkers for diagnosis and prognosis in advanced liver diseases. Either the occurrence of first decompensation, or diagnosis of acute on chronic liver failure, severe alcoholic hepatitis, or hepatocellular carcinoma (HCC), none of the available biomarkers are satisfactory. This review proposes a synthesis of the existing evidences of metabolomics use in advanced chronic liver diseases, decompensated liver cirrhosis, severe alcoholic hepatitis and HCC.
Citation	Procopet B, Fischer P, Farcau O, Stefanescu H. Metabolomics: From liver chiromancy to personalized precision medicine in advanced chronic liver disease. World J Hepatol 2018; 10(3): 371-378

Received	2017-10-29 01:25
Peer-Review Started	2017-10-29 04:58
To Make the First Decision	2017-11-28 08:16
Return for Revision	2017-11-28 09:53
Revised	2017-12-28 15:38
Second Decision	2018-01-24 08:20
Accepted by Journal Editor-in-Chief	2018-01-24 08:39
Accepted by Company Editor-in-Chief	2018-01-29 18:16
Articles in Press	2018-01-29 18:16
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-03-18 13:06

ISSN	1948-5182 (online)
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