Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	37372
Country	United Kingdom

Category	Oncology
Manuscript Type	Review
Article Title	Novel biomarkers for patient stratification in colorectal cancer: A review of definitions, emerging concepts, and data
Manuscript Source	Invited Manuscript
All Author List	Manish Chand, Deborah S Keller, Reza Mirnezami, Marc David Bullock, A Bhangu, BJ Moran, Paris P Tekkis, Gina Brown, Alexander Mirnezami and Mariana Berho
Funding Agency and Grant Number
Corresponding Author	Manish Chand, FRCS (Gen Surg), PhD, Associate Professor, Surgeon, GENIE Centre, University College London, Charles Bell House, 43 Foley Street, London W1W 7TS, United Kingdom. m.chand@ucl.ac.uk
Key Words	Biomarker; Colorectal cancer; Epithelial-to-mesenchymal-transition pathway; Molecular biomarker; MicroRNA; Metabolic biomarker; Imaging biomarker; Tumour regression grade
Core Tip	Biomarkers are an emerging field that can po­tentially guide the diagnosis, prognosis, and treatment course in rectal cancer. Here, the current definitions, classifications, recent developments and emerging bio­markers with potential utility for clinical translation in co­lorectal cancer are reviewed by international experts for a better understanding in surgery.
Citation	Chand M, Keller DS, Mirnezami R, Bullock M, Bhangu A, Moran B, Tekkis PP, Brown G, Mirnezami A, Berho M. Novel biomarkers for patient stratification in colorectal cancer: A review of definitions, emerging concepts, and data. World J Gastrointest Oncol 2018; 10(7): 145-158

Received	2018-03-08 03:39
Peer-Review Started	2018-03-08 08:46
To Make the First Decision	2018-03-19 00:36
Return for Revision	2018-03-19 08:14
Revised	2018-04-22 13:13
Second Decision	2018-06-07 09:29
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2018-06-09 02:23
Articles in Press	2018-06-09 02:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-07-10 00:25

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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