Publication Name	World Journal of Gastroenterology
Manuscript ID	38897
Country	Italy

Category	Anesthesiology
Manuscript Type	Review
Article Title	Perioperative thromboprophylaxis in liver transplant patients
Manuscript Source	Invited Manuscript
All Author List	Lesley De Pietri, Roberto Montalti, Daniele Nicolini, Roberto Ivan Troisi, Federico Moccheggiani and Marco Vivarelli
Funding Agency and Grant Number
Corresponding Author	Lesley De Pietri, MD, Staff Physician, Division of Anaesthesiology and Intensive Care Unit, Department of General Surgery, AUSL Reggio Emilia-IRCCS, Viale Risorgimento 80, Reggio Emilia 42123, Italy. lesley.depietri@yahoo.it
Key Words	Anticoagulation; Liver transplantation; Antiplatelets; Thrombosis; Coagulation; Heparin; Thromboelastography; Thromboprophylaxis; Hepatic artery thrombosis; Portal vein thrombosis
Core Tip	The improvements in surgical and anesthetic techniques during liver transplantation (LT) have led to such a reduction in transfusion requirements that bleeding risk is no longer the major concern. The increased knowledge of coagulation balance and the reported incidence of thrombotic complications (hepatic artery and portal vein thrombosis, intracardiac thrombosis, pulmonary embolism) in the LT setting have brought attention to perioperative thromboprophy­laxis in an attempt to decrease the morbidity and mortality associated with these complications. The major concern of thromboprophylaxis is the risk of bleeding complications in a setting of already unstable hemostasis. Hence, monitoring its administration and the careful selection of the patients to be treated are of great importance.
Citation	De Pietri L, Montalti R, Nicolini D, Troisi RI, Moccheggiani F, Vivarelli M. Perioperative thromboprophylaxis in liver transplant patients. World J Gastroenterol 2018; 24(27): 2931-2948

Received	2018-03-25 08:29
Peer-Review Started	2018-03-25 11:46
To Make the First Decision	2018-04-11 06:44
Return for Revision	2018-04-18 08:51
Revised	2018-05-17 20:16
Second Decision	2018-06-21 09:03
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2018-06-21 17:54
Articles in Press	2018-06-21 17:54
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-07-18 02:46

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected byan in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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