Publication Name	World Journal of Gastroenterology
Manuscript ID	38962
Country	Japan

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Apoptosis and non-alcoholic fatty liver diseases
Manuscript Source	Invited Manuscript
All Author List	Tatsuo Kanda, Shunichi Matsuoka, Motomi Yamazaki, Toshikatsu Shibata, Kazushige Nirei, Hiroshi Takahashi, Tomohiro Kaneko, Mariko Fujisawa, Teruhisa Higuchi, Hitomi Nakamura, Naoki Matsumoto, Hiroaki Yamagami, Hiroo Imazu, Masahiro Ogawa, Kazumichi Kuroda and Mitsuhiko Moriyama
Funding Agency and Grant Number
Corresponding Author	Tatsuo Kanda, MD, PhD, Associate Professor, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Nihon University School of Medicine, 30-1 Oyaguchi-Kamicho, Itabashi-ku 173-8610, Tokyo, Japan. kanda2t@yahoo.co.jp
Key Words	Apoptosis; Autophagy; c-Jun N-terminal kinase; Nonalcoholic fatty liver diseases; Nonalcoholic steatohepatitis
Core Tip	Nonalcoholic fatty liver diseases (NAFLD), including nonalcoholic steatohepatitis (NASH), are one of the most serious health issues. We searched articles written in English and listed on PubMed for the role of apoptosis in NASH. There are close association between apoptosis and NAFLD/NASH. Several inhibitors of apoptosis have been suggested as potential treatments for NASH, and some are now being tested in clinical trials. Therefore, we should focus on the role of apoptosis in the progression of NAFLD/NASH.
Citation	Kanda T, Matsuoka S, Yamazaki M, Shibata T, Nirei K, Takahashi H, Kaneko T, Fujisawa M, Higuchi T, Nakamura H, Matsumoto N, Yamagami H, Ogawa M, Imazu H, Kuroda K, Moriyama M. Apoptosis and non-alcoholic fatty liver diseases. World J Gastroenterol 2018; 24(25): 2661-2672

Received	2018-04-03 01:55
Peer-Review Started	2018-04-03 09:21
To Make the First Decision	2018-05-30 01:22
Return for Revision	2018-06-04 07:14
Revised	2018-06-04 23:33
Second Decision	2018-06-21 09:05
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2018-06-21 17:50
Articles in Press	2018-06-21 17:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-07-03 03:46

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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