Publication Name	World Journal of Diabetes
Manuscript ID	39396
Country	Nigeria

Category	Endocrinology & Metabolism
Manuscript Type	Review
Article Title	Circadian dysrhythmia-linked diabetes mellitus: Examining melatonin’s roles in prophylaxis and management
Manuscript Source	Invited Manuscript
All Author List	Adejoke Yetunde Onaolapo and Olakunle James Onaolapo
Funding Agency and Grant Number
Corresponding Author	Olakunle James Onaolapo, PhD, Professor, Behavioural Neuroscience/Neuropharmacology Unit, Department of Pharmacology, Ladoke Akintola University of Technology, PMB 4400, Osogbo 230263, Osun State, Nigeria. olakunleonaolapo@yahoo.co.uk
Key Words	Chronobiology; Dysmetabolism; Insulin; Pancreatic beta cell; Melatonin receptors
Core Tip	Diabetes mellitus is a chronic, life-threatening metabolic disorder with a huge disease burden and rising global prevalence that is nearing epidemic pr­oportions. Research has continued to reveal the imp­ortance of circadian rhythm and the neurohormone me­latonin in the regulation of carbohydrate metabolism. More studies are also revealing the potential roles of melatonin in the pathogenesis, management and mod­ulation of the course of diabetes mellitus; es­pecially type 2 diabetes mellitus. Presently, an array of potential mechanisms exists for melatonin’s roles in diabetes mellitus; however, a complete picture of this is yet to emerge.
Citation	Onaolapo AY, Onaolapo OJ. Circadian dysrhythmia-linked diabetes mellitus: Examining melatonin’s roles in prophylaxis and management. World J Diabetes 2018; 9(7): 99-114

Received	2018-04-16 01:40
Peer-Review Started	2018-04-16 12:53
To Make the First Decision	2018-05-24 23:52
Return for Revision	2018-05-25 07:32
Revised	2018-06-01 19:03
Second Decision	2018-06-07 11:43
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2018-06-08 23:07
Articles in Press	2018-06-08 23:07
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-07-08 08:31

ISSN	1948-9358 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com