Publication Name	World Journal of Gastroenterology
Manuscript ID	40145
Country	Israel

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Five years of fecal microbiota transplantation - an update of the Israeli experience
Manuscript Source	Unsolicited Manuscript
All Author List	Sharon A Greenberg, Ilan Youngster, Nathaniel A Cohen, Dan M Livovsky, Jacob Strahilevitz, Eran Israeli, Ehud Melzer, Kalman Paz, Naomi Fliss-Isakov and Nitsan Maharshak
Funding Agency and Grant Number
Corresponding Author	Nitsan Maharshak, MD, Chief Doctor, Director, Doctor, Senior Lecturer, Department of Gastroenterology and Liver Diseases & Bacteriotherapy Clinic, Tel Aviv Sourasky Medical Center, 6 Weizmann St., Tel Aviv 6423906, Israel. nitsanm@tlvmc.gov.il
Key Words	Clostridium difficile infection; Capsules; Israel; Fecal microbiota transplantation
Core Tip	Fecal microbiota transplantation (FMT) emerged as a promising treatment for Clostridium difficile infection (CDI). Our aim was to summarize the national Israeli experience in FMT. One-hundred and eleven patients with CDI underwent FMT, 37 (35%) of which via oral capsules and 50 (45%) via colonoscopy. The overall success rate was 87.4%, with no difference between administration routes. Success was independently related to mild disease and an ambulatory setting. One-third of the patients were younger than 60 years. 14 of which (40%) also suffered from inflammatory bowel disease. FMT is an effective treatment for recurrent CDI. FMT via capsules was shown to be a successful alternative to endoscopy.
Citation	Greenberg SA, Youngster I, Cohen NA, Livovsky DM, Strahilevitz J, Israeli E, Melzer E, Paz K, Fliss-Isakov N, Maharshak N. Five years of fecal microbiota transplantation - an update of the Israeli experience. World J Gastroenterol 2018; 24(47): 5403-5414

Received	2018-08-10 05:34
Peer-Review Started	2018-08-10 05:43
To Make the First Decision	2018-10-24 01:50
Return for Revision	2018-10-24 08:17
Revised	2018-11-26 09:17
Second Decision	2018-12-06 10:01
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2018-12-07 03:33
Articles in Press	2018-12-07 03:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-12-20 08:31

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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