Publication Name	World Journal of Gastroenterology
Manuscript ID	42128
Country	Sri Lanka

Category	Gastroenterology & Hepatology
Manuscript Type	Case Control Study
Article Title	Autonomic functions and gastric motility in children with functional abdominal pain disorders
Manuscript Source	Invited Manuscript
All Author List	Amaranath Karunanayake, Shaman Rajindrajith, Hitanadura Asita de Silva, Sampath Gunawardena and Niranga Manjuri Devanarayana
Funding Agency and Grant Number	Funding Agency Grant Number University of Kelaniya RP/03/04/03/01/2013
Corresponding Author	Niranga Manjuri Devanarayana, MBBS, MD, PhD, Professor, Department of Physiology, Faculty of Medicine, University of Kelaniya, Thalagolla Road, Ragama 11010, Sri Lanka. niranga@kln.ac.lk
Key Words	Abdominal pain; Functional gastrointestinal disorders; Autonomic function; Gastric motility
Core Tip	In this study, we examined the relationship between cardiovascular autonomic functions and functional abdominal pain disorders in children. We failed to demonstrate a significant difference in autonomic functions and a significant relationship between gastric motor abnormalities and autonomic functions in affected children. In this paper, we propose functional extrinsic denervation and maladaptive parasympathetic division as possible contributing factors for the impaired gastric motility and symptoms in functional abdominal pain disorders, which is demonstrated in the ‘Automatic Stomach’ model.
Citation	Karunanayake A, Rajindrajith S, de Silva HA, Gunawardena S, Devanarayana NM. Autonomic functions and gastric motility in children with functional abdominal pain disorders. World J Gastroenterol 2019; 25(1): 95-106

Received	2018-09-12 01:56
Peer-Review Started	2018-09-12 04:52
To Make the First Decision	2018-10-24 02:15
Return for Revision	2018-10-26 08:02
Revised	2018-12-01 06:58
Second Decision	2018-12-13 09:06
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2018-12-13 17:43
Articles in Press	2018-12-13 17:43
Publication Fee Transferred
Edit the Manuscript by Language Editor	2018-12-26 01:52
Typeset the Manuscript	2019-01-06 10:19

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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