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Publication Name World Journal of Nephrology
Manuscript ID 42526
Country India
Category Biochemistry & Molecular Biology
Manuscript Type Review
Article Title Insulin receptors in the kidneys in health and disease
Manuscript Source Invited Manuscript
All Author List Sarojini Singh, Rajni Sharma, Manju Kumari and Swasti Tiwari
Funding Agency and Grant Number
Funding Agency Grant Number
Department of Biotechnology, Ministry of Science and Technology, India and Ramalingaswami Grant BT/HRD/35/02/17/2008 (to Tiwari S)
Council of Scientific & Industrial Research, India 09/590/(0159)/2016-EMR-1 (to Sharma R)
Council of Scientific & Industrial Research, India No. 09/590/(0156)/2014-EMR-1 (to Kumari M)
Corresponding Author Swasti Tiwari, PhD, Professor, Department of Molecular Medicine and Biotechnology, Sanjay Gandhi Postgraduate Institute and Chair of Medical Sciences, Lucknow 226014, India. tiwaris@sgpgi.ac.in
Key Words Insulin receptor; Insulin resistance; Kidney disease; Renal sodium reabsorption; Gluconeogenesis; Proteinuria; Systemic blood pressure
Core Tip Dysregulation of the renal insulin receptor (IR) not only affects local renal metabolism, but also disturbs the systemic glucose homeostasis and blood pressure, leading to metabolic abnormalities. The objective of this review is to highlight the pathophysiological stature of renal IRs in the kidney function, as well as, overall metabolism.
Citation Singh S, Sharma R, Kumari M, Tiwari S. Insulin receptors in the kidneys in health and disease. World J Nephrol 2019; 8(1): 11-22
Received
2018-09-28 02:17
Peer-Review Started
2018-09-28 07:56
To Make the First Decision
2018-10-29 02:42
Return for Revision
2018-11-05 09:15
Revised
2018-11-15 07:33
Second Decision
2018-12-07 10:21
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-12-10 21:42
Articles in Press
2018-12-10 21:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-01-15 05:24
ISSN 2220-6124 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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